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Scholar Results 1 - 10 of about 68 citing LEVINE: Suramin antiviral therapy in the acquired immunodeficiency syndrome: Clinical, immunologi.... (0.08 sec) 

Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2 B cells


RJ Coffey, EB Leof, GD Shipley, HL Moses - Journal of cellular physiology, 1987 - interscience.wiley.com
Suramin, a polyanionic compound, has previously been shown to dissociate
platelet-derived growth factor (PDGF) from its receptor. In the present study
suramin was found to inhibit the growth of sparse cultures of AKR-2B cells ...
Cited by 247 - Related articles - All 4 versions

Suramin: an anticancer drug with a unique mechanism of action

- ascopubs.org [PDF] 
CA Stein, RV LaRocca, R Thomas, N McAtee, … - Journal of Clinical Oncology, 1989 - jco.ascopubs.org
From the Medicine Branch, Clinical Oncology Program, National Cancer Institute,
National Institutes of Health, Bethesda, MD. Submitted August 9, 1988; accepted
November 21, 1988. Address reprint requests to Charles E. Myers, MD, Medi- ...
Cited by 245 - Related articles - All 5 versions

Evolving characteristics of AIDS-related lymphoma

- hematologylibrary.org
AM Levine, L Seneviratne, BM Espina, AR … - Blood, 2000 - bloodjournal.hematologylibrary.org
Over time, the epidemiologic and demographic characteristics of AIDS have
changed in the United States. The prevalence of AIDS has increased among
minority populations, in women, and in those who acquired HIV by ...
Cited by 121 - Related articles - BL Direct - All 6 versions

Suramin. A potent inhibitor of melanoma heparanase and invasion

- jbc.org [PDF] 
M Nakajima, A DeChavigny, CE Johnson, J … - Journal of Biological Chemistry, 1991 - ASBMB
Suramin, a polysulfonated naphthylurea, has anti- reverse transcriptase and
anti-proliferative activities and inhibits the binding of various growth factors
to their cell surface receptors. This drug is used in the treatment of ...
Cited by 116 - Related articles - All 4 versions

Suramin, an active drug for prostate cancer: Interim observations in a phase I trial

- oxfordjournals.org [PDF] 
MA Eisenberger, LM Reyno, DI Jodrell, VJ … - JNCI Journal of the National Cancer Institute, 1993 - jnci.oxfordjournals.org
Background: Previous studies indicate that suramin may be an active agent for
treatment of solid tumors. The clinical use of suramin is complicated by a broad
spectrum of toxic effects and complex pharmacology. Studies have suggested ...
Cited by 106 - Related articles - BL Direct - All 8 versions

Suramin therapy in AIDS and related disorders. Report of the US Suramin Working Group


BD Cheson, AM Levine, D Mildvan, LD Kaplan, … - Jama, 1987 - Am Med Assoc
Suramin sodium is a reverse transcriptase inhibitor with in vitro activity
against the human immunodeficiency virus (HIV), the causative agent of acquired
immunodeficiency syndrome (AIDS). Ninety-eight patients with AIDS manifest ...
Cited by 57 - Related articles - All 4 versions

Antifibrotic effects of suramin in injured skeletal muscle after laceration

- physiology.org
YS Chan, Y Li, W Foster, T Horaguchi, G … - Journal of Applied Physiology, 2003 - Am Physiological Soc
Muscle injuries are very common in traumatology and sports medicine. Although
muscle tissue can regenerate postinjury, the healing process is slow and often
incomplete; complete recovery after skeletal muscle injury is hindered by ...
Cited by 44 - Related articles - BL Direct - All 5 versions

Suramin in hormone-refractory metastatic prostate cancer: a drug with limited efficacy

- jcojournal.org [PDF] 
PJ Rosen, EF Mendoza, EM Landaw, B Mondino … - Journal of Clinical Oncology, 1996 - jcojournal.org
Purpose: To confirm the previously reported high re- sponse rates and prolonged
survival in hormone-refractory prostate cancer treated with suramin. Patients
and Methods: Thirty-six eligible patients with hormone-refractory prostate ...
Cited by 40 - Related articles - BL Direct - All 7 versions

The use of suramin, an antifibrotic agent, to improve muscle recovery after strain injury


YS Chan, Y Li, W Foster, FH Fu, J Huard - The American journal of sports medicine, 2005 - ajsm.highwire.org
Materials and Methods: In vitro, muscle-derived fibroblasts (a potential cell
source of muscle fibrosis) were incubated with suramin and/or transforming
growth factor–β1; a cell growth curve was obtained. In vivo, mouse ...
Cited by 39 - Related articles - All 10 versions

Impairment of adrenocortical function associated with increased plasma tumor necrosis …


M Reincke, C Heppner, F Petzke, B Allolio, … - Neuroimmunomodulation, 1994 - content.karger.com
African sleeping sickness (SS) is a severe, potentially lethal parasitic
disease. The treatments of choice are the antiparasitic agents suramin, which is
adrenotoxic, and/or melarsoprol. We evaluated the functional integrity of ...
Cited by 38 - Related articles - All 4 versions


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