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Scholar Results 1 - 10 of about 46 citing KURZROCK: Rearrangement in the breakpoint cluster region and the clinical course in Philadelphia-.... (0.08 sec) 

Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular …

- annals.org [PDF] 
R Kurzrock, HM Kantarjian, BJ Druker, M … - Annals of internal medicine, 2003 - Am Coll Physicians
The Philadelphia chromosome translocation (t(9;22)) results in the molecular
juxtaposition of two genes, BCR and ABL, to form an aberrant BCR-ABL gene on
chromosome 22. BCR-ABL is critical to the pathogenesis of chronic ...
Cited by 121 - Related articles - BL Direct - All 10 versions

Translocation of BCR to chromosome 9: a new cytogenetic variant detected by FISH in two …


A Hagemeijer, A Buijs, E Smit, B Janssen, GJ … - GENES CHROMOSOMES AND CANCER, 1993 - interscience.wiley.com
Leukemic cells from two patients with Philadelphia-negative chronic myeloid
leukemia (CML) were investigated: I) Cytogenetics showed a normal 46.XY
karyotype in both cases, 2) molecular studies revealed rearrangement of the ...
Cited by 81 - Related articles - BL Direct - All 2 versions

Philadelphia chromosome-negative chronic myelogenous leukemia without breakpoint cluster …

- hematologylibrary.org [PDF] 
R Kurzrock, HM Kantarjian, M Shtalrid, JU … - Blood, 1990 - bloodjournal.hematologylibrary.org
HE KARYOTYPIC hallmark of chronic myelogenous T leukemia (CML) is a shortened
chromosome 22, desig- ... From the Department of Clinical Immunology and
Biological Therapy and the Department of Hematology, The University of ...
Cited by 79 - Related articles - All 4 versions

Clinical course and therapy of chronic myelogenous leukemia with interferon-alpha and …


HM Kantarjian, FJ Giles, SM O'Brien, M … - Hematology/oncology clinics of North America, 1998 - Elsevier
The prognosis for patients with chronic myelogenous leukemia (CML) has changed
markedly since 1856, when the use of arsenicals (Fowler's solution) was first
advocated in this condition. 154 In the early 1900s, systemic or splenic ...
Cited by 71 - Related articles - BL Direct - All 5 versions

Expression of c-abl in Philadelphia-positive acute myelogenous leukemia

- bloodjournal.org [PDF] 
R Kurzrock, M Shtalrid, M Talpaz, WS … - Blood, 1987 - Am Soc Hematology
. Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ...
Cited by 49 - Related articles - All 6 versions

[PDF] Chronic myelogenous leukemia as a paradigm of early cancer and possible curative …


B Clarkson, A Strife, D Wisniewski, CL Lambek … - Leukemia, 2003 - hep.uchicago.edu
The chronological history of the important discoveries leading to our present
understanding of the essential clinical, biologi- cal, biochemical, and
molecular features of chronic myelogen- ous leukemia (CML) are first ...
Cited by 45 - Related articles - View as HTML - BL Direct - All 7 versions

BCR rearrangement-negative chronic myelogenous leukemia revisited

- ascopubs.org
R Kurzrock, CE Bueso-Ramos, H Kantarjian, E … - Journal of Clinical Oncology, 2001 - jco.ascopubs.org
Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg
Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this? ...
From the Departments of Leukemia, Bioimmunotherapy, Pathology, ...
Cited by 39 - Related articles - BL Direct - All 6 versions

Do oncogenes determine clinical features in chronic myeloid leukaemia?


O Dreazen, F Rassool, RS Sparkes, I Klisak, … - The Lancet, 1987 - Elsevier
Oncogene abnormalities are thought to have a central role in some human
malignant disorders, particularly Burkitt leukaemia/ lymphoma and chronic
myeloid leukaemia (CML). However, the extent to which specific oncogene ...
Cited by 36 - Related articles - All 4 versions

Significance and correlations of molecular analysis results in patients with …


HM Kantarjian, M Shtalrid, R Kurzrock, M … - The American Journal of Medicine, 1988 - Elsevier
Rearrangement of the breakpoint cluster region (bcr) was detected in 11 of the
23 patients with Ph-negative CML (48 percent), indicating the presence of the
abnormal molecular events in Ph-positive CML without documentation of the ...
Cited by 29 - Related articles - All 7 versions

Recombinant interferon-alpha therapy of Philadelphia chromosome-negative …


M Talpaz, R Kurzrock, H Kantarjian, S O' … - The American journal of medicine, 1989 - Elsevier
Recombinant Interferon-Alpha Therapy of Philadelphia Chromosome-Negative
Myeloproliferative Disorders with Thrombocytosis MOSHE TALPAZ, MD, RAZELLE
KURZROCK, MD, HAGOP KANTARJIAN, MD, SUSAN O'BRIEN, MD, JORDAN U. GUTTERMAN, ...
Cited by 24 - Related articles - All 6 versions


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