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Scholar Results 1 - 10 of about 965 citing Cross: Oxygen radicals and human disease. (0.12 sec) 

[PDF] Ascorbate is an outstanding antioxidant in human blood plasma


B Frei, L England, BN Ames - Proceedings of the National …, 1989 - National Acad Sciences
Page 1. Proc. Nati. Acad. Sci. USA Vol. 86, pp. 6377-6381, August 1989 Medical Sciences
Ascorbate is an outstanding antioxidant in human blood plasma (oxidant stress/lipid
peroxidation/protein thiols/a-tocopherol) BALZ FREI, LAURA ENGLAND, AND BRUCE N. AMES* ...
Cited by 1053 - Related articles - All 8 versions

Reactive oxygen species in cell signaling

- physiology.org
VJ Thannickal, BL Fanburg - American Journal of Physiology- …, 2000 - Am Physiological Soc
Reactive oxygen species (ROS) are generated as by-products of cellular metabolism, primarily
in the mitochondria. When cellular production of ROS overwhelms its antioxidant capacity, damage
to cellular macromolecules such as lipids, protein, and DNA may ensue. Such a state of " ...
Cited by 844 - Related articles - BL Direct - All 7 versions

High stored iron levels are associated with excess risk of myocardial infarction in …

- ahajournals.org [PDF] 
JT Salonen, K Nyyssonen, H Korpela, J Tuomilehto, R … - Circulation, 1992 - Am Heart Assoc
Background. Iron can induce lipid peroxidation in vitro and in vivo in humans and has promoted
ischemic myocardial injury in experimental animals. We tested the hypothesis that high serum
ferritin concentration and high dietary iron intake are associated with an excess risk of ...
Cited by 730 - Related articles - All 5 versions

The oxidant stress hypothesis in Parkinson's disease: evidence supporting it


S Fahn, G Cohen - Annals of neurology, 1992 - interscience.wiley.com
Oxidant stress, due to the formation of hydrogen peroxide and oxygen-derived free radicals,
can cause cell damage due to chain reactions of membrane lipid peroxidation. Because the
substantia nigra is rich in dopamine, which can undergo both enzymatic oxidation via ...
Cited by 612 - Related articles - BL Direct - All 3 versions

Deactivation of macrophages by transforming growth factor-β


S Tsunawaki, M Sporn, A Ding, C Nathan - 1988 - nature.com
Macrophage activation—enhanced capacity to kill, in a cell that otherwise mostly
scavenges—is essential for host survival from infection and contributes to containment of
tumours. Both microbes and tumour cells, therefore, may be under pressure to inhibit or ...
Cited by 602 - Related articles - All 4 versions

[PDF] The lipids


JR Sargent, RJ Henderson, DR Tocher - Fish nutrition, 1989 - kogi.udea.edu.co
4.1. Introduction 4.2. Structures and Biosynthesis 4.2.1. Lipid Classes: Structures 4.2.2. Fatty
Acid Structures 4.2.3. Fatty Acid Biosynthesis 4.2.4. Lipid Class Biosynthesis 4.3. Functions
4.3.1. Energy Production 4.3.2. Membrane Structure and Functions 4.4. Fatty Acids and ...
Cited by 564 - Related articles - View as HTML - All 2 versions

The chemistry and antioxidant properties of tocopherols and tocotrienols


A Kamal-Eldin, LÅ Appelqvist - Lipids, 1996 - Springer
Lipid oxidation is a degradative, free radical mediated process responsible for the development
of objectionable odors and flavors in oils, fats, and foods containing them (1-7). Moreover, oxidation
of the polyunsaturated fatty acids (PUFA) of the biomembranes causes functional ...
Cited by 526 - Related articles - BL Direct - All 4 versions

Production of hydroxyl radicals from the simultaneous generation of superoxide …

- nih.gov [PDF] 
N Hogg, VM Darley-Usmar, MT Wilson, S … - Biochemical …, 1992 - pubmedcentral.nih.gov
B"oth nitric oxide (NO) and superoxide are generated by macrophages, neutrophils and endothelial
cells. It has been postulated that the generation of these two radicals under physiological conditions
can lead to the formation of peroxyintritne and (as a result of the homolytic lysis of this ...
Cited by 516 - Related articles - All 7 versions

The American-European consensus conference on ARDS, part 2

- 171.66.122.149
A Artigas, GR Bernard, J Carlet, D Dreyfuss, L … - Intensive Care Medicine, 1998 - Springer
Abstract The acute respiratory dis- tress syndrome (ARDS) continues as a contributor to the morbidity
and mortality of patients in intensive care units throughout the world, im- parting tremendous
human and fi- nancial costs. During the last ten years there has been a decline in ARDS ...
Cited by 493 - Related articles - BL Direct - All 9 versions

The role of oxidative stress in the onset and progression of diabetes and its …


P Rösen, PP Nawroth, G King, W Möller, HJ … - Diabetes/Metabolism … - interscience.wiley.com
This review summarises the results and discussions of an UNESCO-MCBN supported symposium
on oxidative stress and its role in the onset and progression of diabetes. There is convincing
experimental and clinical evidence that the generation of reactive oxygen species (ROI) is ...
Cited by 345 - Related articles - BL Direct - All 3 versions


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