HJ Adrogue, NE Madias - The New England journal of medicine, 2000 - nejm.highwire.org Hyponatremia is defined as a decrease in the serum sodium concentration to a level below 136
mmol per liter. Whereas hypernatremia always denotes hypertonicity, hyponatremia can be associated
with low, normal, or high tonicity. 1 , 2 Effective osmolality or tonicity refers to the ... Cited by 484 - Related articles - All 5 versions
- ►asnjournals.org [PDF] RH Sterns, JD Cappuccio, SM Silver, EP … - Journal of the American …, 1994 - Am Soc Nephrol Page 1. 1522 Volume 4 #{149}Number 8 #{149}1994 Neurologic Sequelae After Treatment of
Severe Hyponatremia: A Multicenter Perspective' Richard H. Sterns,2 Joseph D. Cappuccio,
Stephen M. Silver, and Eric P. Cohen PH. Sterns, JD Cappuccio, SM. Silver, University of ... Cited by 158 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] YH Lien, JI Shapiro, L Chan - Journal of Clinical Investigation, 1991 - pubmedcentral.nih.gov Osmotic injury induced by rapid correction ofsevere chronic hyponatremia has been implicated
in the development of cen- tral pontinemyelinolysis. Organic osmolytes known previously as
"idiogenic osmoles" accumulate intracellularly to protect cells from osmotic injury. We ... Cited by 125 - Related articles - All 8 versions
JC Ayus, AI Arieff - Jama, 1999 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. ... Add to CiteULike Add to Connotea Add to ... Cited by 109 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] JS Videen, T Michaelis, P Pinto, BD … - Journal of Clinical …, 1995 - pubmedcentral.nih.gov The pathogenesis of morbidity associated with hypona- tremia is postulated to be determined
by the state of intracel- lular cerebral osmolytes. Previously inaccessible, these me- tabolites
can now be quantitated by proton magnetic reso- nance spectroscopy. An in vivo ... Cited by 103 - Related articles - BL Direct - All 9 versions
JE Brunner, JM Redmond, AM Haggar, DF … - Annals of …, 1990 - interscience.wiley.com The rate at which profound hyponatremia should be corrected is the focus of a recent clinical
debate. We prospectively studied neurological outcomes with serial magnetic resonanace imaging
in 13 hyponatremic subjects with serum sodium concentrations of less than 115 mmol/L ( ... Cited by 95 - Related articles - All 3 versions
RH Sterns, DJ Thomas, RM Herndon - Kidney Int, 1989 - nature.com Brain dehydration and neurologic deterioration after rapid correction of hyponatremia. We made
rats severely hyponatremia varying the rate of onset and duration of the disturbance, and then
compared rapid correction to slow correction. An acute fall in the plasma Na to 106 ... Cited by 87 - Related articles - All 4 versions
R Laureno, I Karp… - The Lancet, 1988 - Elsevier Central pontine and extrapontine myelinolysis is caused by the rapid correction of
hyponatraemia. Acceptance of this concept has been impeded by recent reports attributing myelinolysis
to uncorrected hyponatraemia, overcorrection of hyponatraemia, or hypoxia. Several new ... Cited by 73 - Related articles - All 6 versions