G Tsai, DR Gastfriend, JT Coyle - American Journal of Psychiatry, 1995 - Am Psychiatric Assoc Page 1. 332 AmJ Psychiatry 152:3, March 1995 Special Article The Glutamatergic
Basis of Human Alcoholism Guochuan Tsai, MD, Ph.D., David R. Gastfriend, MD,
and Joseph T. Coyle, MD Objective: Although alcoholism is ... Cited by 226 - Related articles - All 6 versions
RM Swift - The New England journal of medicine, 1999 - nejm.highwire.org There is increasing interest in drug therapy for alcohol dependence. 6 , 7 , 8 The rationale for
such therapy is based on several premises. First, advances in neurobiology have identified neurotransmitter
systems that initiate and maintain the drinking of alcohol; pharmacologic modification of ... Cited by 153 - Related articles - BL Direct - All 8 versions
CD Spies, H Rommelspacher - Anesthesia & Analgesia, 1999 - anesthanalg.org Alcohol is the most abused drug worldwide (1). In the United States, the apparent per capita
consumption of ethanol from all alcoholic beverage types combined was 2.21 gallons pure ethanol
in 1994 (2). In 1996, 109 million Americans aged 12 yr had used alcohol in the last month ... Cited by 77 - Related articles - BL Direct - All 12 versions
RZ Litten, JP Allen - Alcohol Clin Exp Res, 1991 - interscience.wiley.com The past 10 years have witnessed important advances in research on pharmacotherapy for
alcoholism. Promising drugs are discussed under six headings: agents to treat alcohol
withdrawal; anticraving agents; agents that make drinking an aversive experience; agents ... Cited by 75 - Related articles - All 4 versions
CD Spies, NRA Dubisz, T Neumann, S Blum, C … - Critical care …, 1996 - journals.lww.com From the Department of Anesthesiology and Operative Intensive Care Medicine (Drs. Spies,
Neumann, Brummer, Specht, Sanft, Hannemann, Striebel, and Schaffartzik, and Mr. Dubisz)
and the Department of Neurology (Dr. Blum), Benjamin Franklin Medical Center; the ... Cited by 70 - Related articles - BL Direct - All 3 versions
P De Witte, E Pinto, M Ansseau, P Verbanck - Neuroscience and biobehavioral …, 2003 - Elsevier The withdrawal syndrome in alcohol-dependent patients appears to be a major stressful event
whose intensity increases with repetition of detoxifications according to a kindling process. Disturbances
in the balance between excitatory and inhibitory neural processes are reflected in a ... Cited by 67 - Related articles - All 5 versions
- ►wisc.edu [PDF] S Rassnick, GF Koob, MA Geyer - Psychopharmacology, 1992 - Springer Abstract. Ethanol (EtOH) withdrawal is characterized by a hyperexcitable state that includes
anxiety, tremor, mus- cle rigidity and seizures. The present three experiments examined the effects
of EtOH dependence and with- drawal on the acoustic startle response, an easily quan- ... Cited by 59 - Related articles - All 6 versions
- ►nih.gov [PDF] CS Lieber, E Baraona, R Hernandez- … - Journal of Clinical …, 1989 - pubmedcentral.nih.gov The role of oxygenation in the pathogenesis of alcoholic liver injury was investigated in six baboons
fed alcohol chronically and in six pair-fed controls. All animals fed alcohol developed fatty liver
with, in addition, fibrosis in three. No evidence for hypoxia was found, bothin the basal ... Cited by 55 - Related articles - All 5 versions
HC Becker - Psychopharmacology, 1994 - Springer Abstract. One factor that has been shown to influence the severity of an ethanol withdrawal syndrome
is a history of prior experience with episodes of ethanol withdrawal. It has been hypothesized
that the progressive intensification of withdrawal symptoms following repeated bouts of ... Cited by 52 - Related articles - BL Direct - All 3 versions