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Scholar Results 1 - 10 of about 77 citing STACPOOLE: Dichloroacetate in the treatment of lactic acidosis. (0.08 sec) 

Lactic acidosis in critical illness


BA MIZOCK, JAYL FALK - Critical care medicine, 1992 - journals.lww.com
Criticai. Care Mkdicine Copyright © 1992 by Williams & Wilkins Voi. 20, No. 1
Printed in USA Lactic acidosis in critical illness BARRY A. MIZOCK, MD, FACP;
JAY L. FALK, MD, FCCM Purpose: This article reviews the current body of ...
Cited by 362 - Related articles - All 4 versions

Sodium Bicarbonate for the Treatment of Lactic Acidosis*


SM Forsythe, GA Schmidt - Chest, 2000 - chestjournal.chestpubs.org
Lactic acidosis often challenges the intensivist and is associated with a
strikingly high mortality. Treatment involves discerning and correcting its
underlying cause, ensuring adequate oxygen delivery to tissues, reducing ...
Cited by 137 - Related articles - BL Direct - All 6 versions

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes …

- puredca.com [PDF] 
S Bonnet, SL Archer, J Allalunis-Turner, A … - Cancer cell, 2007 - Elsevier
The unique metabolic profile of cancer (aerobic glycolysis) might confer
apoptosis resistance and be therapeutically targeted. Compared to normal cells,
several human cancers have high mitochondrial membrane potential (ΔΨm) ...
Cited by 139 - Related articles - All 23 versions

Biguanide-associated lactic acidosis: case report and review of the literature


SC Gan, J Barr, AI Arieff, RG Pearl - Archives of Internal Medicine, 1992 - archinte.highwire.org
Page 1. Biguanide-Associated Lactic Acidosis Case Report and Review of
the Literature Sandra C. Gan, MD; Juliana Barr, MD; Allen ...
Cited by 102 - Related articles - BL Direct - All 5 versions

Adjunctive therapies in sepsis: an evidence-based review

- critcaremed.com
A Cariou, C Vinsonneau, JF Dhainaut - Critical care medicine, 2004 - journals.lww.com
Objective: In 2003, critical care and infectious disease experts representing 11
international organizations developed management guidelines for adjunctive
therapies in sepsis that would be of practical use for the bedside ...
Cited by 63 - Related articles - BL Direct - All 13 versions

Sodium bicarbonate in the treatment of subtypes of acute lactic acidosis: physiologic …


BJ Hindman - Anesthesiology, 1990 - journals.lww.com
MEDICAL INTELLIGENCE ARTICLE Julien F. Biebuyck, MB, D.Phil., Editor
Anesthesiology 72:1064-1076, 1990 Sodium Bicarbonate in the Treatment of
Subtypes of Acute Lactic Acidosis: Physiologic Considerations Bradley J. ...
Cited by 53 - Related articles - All 3 versions

Lactic and hydrochloric acids induce different patterns of inflammatory response in LPS- …

- physiology.org
JA Kellum, M Song, J Li - … Journal of Physiology- Regulatory, Integrative and …, 2004 - Am Physiological Soc
Metabolic acidosis frequently complicates sepsis and septic shock and may be
deleterious to cellular function. Different types of metabolic acidosis (eg,
hyperchloremic and lactic acidosis) have been associated with different ...
Cited by 53 - Related articles - BL Direct - All 5 versions

Dichloroacetate as metabolic therapy for myocardial ischemia and failure*


RM Bersin, PW Stacpoole - American Heart Journal, 1997 - Elsevier
This article critically reviews the pharmacologic effects of the investigational
drug dichloroacetate (DCA), which activates the mitochondrial pyruvate
dehydrogenase enzyme complex in cardiac tissue and thus preferentially ...
Cited by 51 - Related articles - BL Direct - All 5 versions

Dichloroacetate reduces sympathetic nerve responses to static exercise


S Ettinger, K Gray, S Whisler, L Sinoway - American Journal of Physiology- Heart and Circulatory …, 1991 - Am Physiological Soc
ETTINGER, STEVEN, KRISTEN GRAY, SANDRA WHISLER, AND LAWRENCE SINOWAY.
Dichloroacetate reduces sympathetic nerve responses to static exercise. Am. J.
Physiol. 261 (Heart Circ. Physiol. 30): Hl653-Hl658,1991.-Lactic acid is ...
Cited by 41 - Related articles - All 3 versions

FAILURE OF MONOCHLOROACETIC ACID AND TRICHLOROACETIC ACID ADMINISTERED …


AB DeAngelo, F Bernard, D Bernard, M Most, … - Journal of toxicology and environmental health, 1997 - ingentaconnect.com
The chlorinated acetic acids monochloroacetic acid MCA and trichloroacetic acid
TCA are found as chlorine disinfection by-products in finished drinking-water
supplies. TCA has been demonstrated to be a mouse liver carcinogen. A ...
Cited by 40 - Related articles - BL Direct - All 6 versions


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