- ►sbinfecto.org.br [PDF] A Carr, DA Cooper - The Lancet, 2000 - Elsevier Several factors have combined to increase our attention on the toxicity of
HAART. First, since HIV-1 eradication seems unlikely with current therapy, 1 and
2 HAART will need to be indefinite for clinical benefits to be preserved. ... Cited by 701 - Related articles - BL Direct - All 11 versions
CS Crumpacker - The New England Journal of Medicine, 1996 - nejm.highwire.org Ganciclovir is a nucleoside analogue of guanosine, a homologue of acyclovir, and
the first antiviral drug to be effective in the treatment of cytomegalovirus
(CMV) disease in humans. 1 , 2 , 3 , 4 It inhibits not only all the ... Cited by 256 - Related articles - All 4 versions
DC Musch, DF Martin, JF Gordon, MD Davis, … - The New England journal of medicine, 1997 - nejm.highwire.org Results The median time to progression of retinitis was 221 days with the
1-µg-per-hour implant (75 eyes), 191 days with the 2-µg-per-hour implant (71
eyes), and 71 days with ganciclovir administered intravenously (76 eyes; ... Cited by 156 - Related articles - BL Direct - All 8 versions
DA Jabs - Transactions of the American Ophthalmological Society, 1995 - pubmedcentral.nih.gov OBJECTIVE: To evaluate the frequency of ocular complications and the clinical
outcomes of these complications in patients with various stages of HIV
infection. METHODS: Retrospective review of all HIV-infected patients seen ... Cited by 139 - Related articles - BL Direct - All 4 versions
SC Piscitelli, C Flexner, JR Minor, MA Polis, … - Clinical infectious diseases, 1996 - jstor.org Patients with AIDS who are receiving optimal medical care, including combination
therapy with antiretroviral agents and more effective prophylaxis and therapy
for opportunistic infections and neoplasms, are surviving longer. However, ... Cited by 127 - Related articles - BL Direct - All 3 versions
JP Lalezari, WL Drew, E Glutzer, C James, D … - The Journal of Infectious Diseases, 1995 - jstor.org CMV effect was observed with all cidofovir regimens ^3.0 mg/kg. The
dose-limiting toxicity of cidofovir was dose- and schedule-dependent
nephrotoxicity. Four of 20 patients had serum creati- nine levels 5*2.0 ... Cited by 88 - Related articles - BL Direct - All 3 versions
DT Dieterich, MA Poles, EA Lew, PE Mendez, … - The Journal of infectious diseases, 1993 - jstor.org Ten patients with AIDS and progressive cytomegalovirus disease were treated with
ganciclovir and foscarnet concurrently. The patients had received ganciclovir
and foscarnet monotherapy a median of 330 days before receiving combination ... Cited by 63 - Related articles - BL Direct - All 3 versions
- ►jbc.org M Adachi, J Sampath, L Lan, D Sun, P … - Journal of Biological Chemistry, 2002 - ASBMB The multidrug resistance protein MRP4, a member of the ATP-binding cassette
superfamily, confers resistance to purine-based antiretroviral agents. However,
the antiviral agent ganciclovir (GCV) has not been shown to be a substrate ... Cited by 58 - Related articles - BL Direct - All 4 versions
- ►annals.org HC Lane, BE Laughon, J Falloon, JA Kovacs, … - Annals of internal medicine, 1994 - Am Coll Physicians Secondary infections remain the leading cause of death in patients with the
acquired immunodeficiency syndrome (AIDS).Dealing with the rapidly evolving
spectrum of infectious problems seen in patients with AIDS requires ... Cited by 51 - Related articles - BL Direct - All 4 versions
