- ►nih.gov [PDF] T Münzel, H Sayegh, BA Freeman, MM … - Journal of Clinical …, 1995 - pubmedcentral.nih.gov We sought to examine mechanisms underlying nitroglycerin (NTG) tolerance and
"cross-tolerance" to other nitrovaso- dilators. Rabbits were treated for 3 d with NTG patches
(0.4 mg/h) and their aortic segments studied in organ chambers. Relaxations were ... Cited by 522 - Related articles - BL Direct - All 8 versions
JD Parker, JO Parker - New England Journal of Medicine, 1998 - content.nejm.org The organic nitrates are widely used in the management of coronary artery disease. They are
given not only to patients with stable angina pectoris, but also to those with unstable angina,
acute myocardial infarction, and heart failure. Although they are effective for the treatment ... Cited by 345 - Related articles - BL Direct - All 7 versions
- ►pnas.org [PDF] T Münzel, A Giaid, S Kurz, DJ Stewart, … - Proceedings of the …, 1995 - National Acad Sciences Page 1. Proc. Natl. Acad. Sci. USA Vol. 92, pp. 5244-5248, May 1995 Medical Sciences
Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance
THOMAS MUNZEL*, ADEL GLAIDt, SABINE KURZ*, DUNCAN ... Cited by 144 - Related articles - BL Direct - All 9 versions
[CITATION] Chronic ischemic heart disease
JD Rutherford, E Braunwald, PF Cohn - Heart disease: a textbook of …, 1992 - WB Saunders Cited by 136 - Related articles
GE McVeigh, GM Brennan, GD Johnston, BJ … - Diabetologia, 1993 - Springer Summary. Decreased release of nitric oxide from damaged endothelium is responsible for the
impaired endothelium-de- pendent vasodilator responses found in animal models of vascular
disease. Dietary supplementation with fish oils has been shown to augment endothelium- ... Cited by 120 - Related articles - BL Direct - All 4 versions
JP Stasch, P Schmidt, C Alonso-Alija, H … - British Journal of …, 2002 - pubmedcentral.nih.gov Soluble guanylyl cyclase (sGC) is the only proven receptor for the ubiquitous biological messenger
nitric oxide (NO) and is intimately involved in many signal transduction pathways, most notably
in regulating vascular tone and platelet function. sGC is a heterodimeric (α/ß) protein that ... Cited by 109 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org [PDF] PW Armstrong, GW Moe - Circulation, 1993 - Am Heart Assoc The increased incidence and prevalence of congestive heart failure place a high priority on novel ... J3-receptor population, with resultant improved contractile performance, enhanced myocardial
relaxation, ... (Circulation. 1994;88:2941-2952.) KEY WORDs * heart failure, congestive * ... Cited by 107 - Related articles - BL Direct - All 5 versions
T Münzel, S Kurz, T Heitzer, DG Harrison - The American journal of cardiology, 1996 - Elsevier The hemodynamic and anti-ischemic efficacy of organic nitrates is rapidly blunted due to the
development of nitrate tolerance. The mechanisms underlying this phenomenon remain poorly
understood and likely involve several independent factors. More recent experimental ... Cited by 93 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org H Watanabe, M Kakihana, S Ohtsuka, Y Sugishita - Circulation, 1997 - Am Heart Assoc Methods and Results In this double-blind, placebo-controlled study, 24 normal volunteers and
24 patients with ischemic heart disease (IHD patients) were randomized to receive either vitamin
E (200 mg TID vitamin E group) or placebo (placebo group). Vasodilator response to ... Cited by 90 - Related articles - BL Direct - All 7 versions
