R Hambrecht, J Niebauer, E Fiehn, B Kälberer, B … - Journal of the American …, 1995 - Elsevier After 6 months, patients in the training group achieved an increase in oxygen uptake at the ventilatory
threshold of 23% (from 0.86 ± 0.2 to 1.07 ± 0.2 liters/min, p < 0.01 vs. control group) and at peak
exercise of 31% (from 1.49 ± 0.4 to 1.95 ± 0.4 liters/min, p < 0.01 vs. control group). There ... Cited by 378 - Related articles - BL Direct - All 8 versions
IL Pina, CS Apstein, GJ Balady, R Belardinelli, BR … - Circulation, 2003 - Am Heart Assoc Exercise intolerance is defined as the reduced ability to perform activities that involve dynamic
movement of large skeletal muscles because of symptoms of dyspnea or fatigue. Many investigators
have sought mechanisms to explain the source of exercise intolerance. The aims of this ... Cited by 249 - Related articles - BL Direct - All 12 versions
R Hambrecht, MD, E Fiehn, MD, J Yu, MD, J … - Journal of the American …, 1997 - Elsevier Objectives. The present study was designed to evaluate the effects of an ambulatory training
program in patients with chronic heart failure (CHF) on the ultrastructural morphology of mitochondria
and fiber type distribution of skeletal muscle and its relation to peripheral perfusion. Cited by 206 - Related articles - BL Direct - All 5 versions
SJ Keteyian, C Brawner - Heart Failure Reviews, 1999 - Springer Abstract. Historically, patients with heart failure were ad- vised to avoid exertion due to fear that
the added myocar- dial stress would worsen heart function. However, between 1979 and
1991, ~ve uncontrolled trials demonstrated that moderate exercise training can partially ... Cited by 177 - Related articles - BL Direct - All 7 versions
- ►annals.org J Myers, L Gullestad, R Vagelos, D Do, D … - Annals of internal …, 1998 - Am Coll Physicians Background: Accurate prognosis in chronic heart failure has become increasingly important in
assessing the efficacy of treatment and in appropriately allocating scarce resources for
transplantation. Previous studies of severe heart failure have been limited by short ... Cited by 179 - Related articles - BL Direct - All 5 versions
RS McKelvie, KK Teo, N McCartney, D Humen, T … - Journal of the American …, 1995 - Elsevier Congestive heart failure is a potentially debilitating disorder that affects a significant number
of patients. The age-adjusted death rate has doubled over the past decade. Patients live an average
of 4 to 5 years, and nearly all suffer from fatigue and breathlessness, which limits exercise ... Cited by 162 - Related articles - BL Direct - All 5 versions
- ►onlinejacc.org WG Hundley, DW Kitzman, TM Morgan, CA … - Journal of the American …, 2001 - Elsevier Aortic compliance declines substantially with age. We hypothesized that a reduction in cardiac
cycle-dependent changes in thoracic aortic area and distensibility (above that which occurs with
aging) could be associated with the exercise intolerance that is prominent in elderly ... Cited by 138 - Related articles - BL Direct - All 12 versions
P Dubach, MD, J Myers, PhD, FACC, G Dziekan, … - Journal of the American …, 1997 - Elsevier Methods. Twenty-five men with left ventricular dysfunction after a myocardial infarction or coronary
artery bypass graft surgery were randomized to an exercise training group (mean age ± SD 56
± 5 years, mean ejection fraction [EF] 32 ± 7%, n = 12) or a control group (mean age 55 ± ... Cited by 128 - Related articles - BL Direct - All 7 versions
- ►onlinejacc.org R Hambrecht, V Adams, S Gielen, A Linke, S … - Journal of the American …, 1999 - Elsevier Methods. Thirty-eight patients with CHF and 8 healthy controls (C) underwent bicycle ergospirometry
and biopsy of the vastus lateralis muscle. Expression of iNOS was quantified by immunohistochemistry
and reverse-transcriptase polymerase chain reaction, mi-CK by Western-blot. Intracellular ... Cited by 115 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org M Guazzi, G Marenzi, M Alimento, M Contini, P … - Circulation, 1997 - Am Heart Assoc Methods and Results In 16 CHF patients and 16 normal volunteers or mild untreated
hypertensives, pulmonary function and exercise tests with respiratory gas analysis were assessed
on placebo, enalapril (10 mg BID), enalapril plus aspirin (325 mg/d), or aspirin, in random ... Cited by 107 - Related articles - BL Direct - All 5 versions
