- ►rupress.org RPM Sutmuller, LM van Duivenvoorde, A van … - Journal of Experimental …, 2001 - jem.rupress.org Therapeutic efficacy of a tumor cell–based vaccine against experimental B16 melanoma requires the
disruption of either of two immunoregulatory mechanisms that control autoreactive T cell responses:
the cytotoxic T ... Cited by 637 - Related articles - BL Direct - All 5 versions
OW Press, JF Eary, FR Appelbaum, PJ Martin, … - New England Journal …, 1993 - content.nejm.org Methods Sequential biodistribution studies were performed with escalating doses of antibody (0.5,
2.5, and 10 mg per kilogram of body weight) trace-labeled with 5 to 10 mCi of 131 I. The doses of
radiation absorbed by tumors and ... Cited by 549 - Related articles - BL Direct - All 7 versions
- ►hematologylibrary.org - Free from Publisher DC Matthews, FR Appelbaum, JF Eary, DR … - …, 1999 - bloodjournal.hematologylibrary.org Delivery of targeted hematopoietic irradiation using radiolabeled monoclonal antibody may improve
the outcome of marrow transplantation for advanced acute leukemia by decreasing relapse without
increasing toxicity. We conducted a ... Cited by 218 - Related articles - BL Direct - All 5 versions
- ►ascopubs.org [PDF] RO Dillman - Journal of Clinical Oncology, 1994 - jco.ascopubs.org Purpose: This review was conducted to characterize the results of trials of unconjugated monoclonal
antibod- ies in the treatment of cancer. This survey does not cover antibodies conjugated to drugs,
isotopes, or toxins. Methods: An ... Cited by 139 - Related articles - BL Direct - All 6 versions
W Debinski, NI Obiri, I Pastan, RK Puri - Journal of Biological Chemistry, 1995 - ASBMB Chimeric proteins provide a unique opportunity to target therapeutic bacterial toxins to a subset of
specific cells. We have generated a new recombinant chimeric toxin composed of human interleukin 13
(hIL13) and a Pseudomonas exotoxin ... Cited by 133 - Related articles - BL Direct - All 4 versions
AE Frankel, RJ Kreitman, EA Sausville - Clinical Cancer Research, 2000 - AACR Targeted toxins consist of a targeting polypeptide covalently linked to a peptide toxin. The
targeting protein may be an antibody or antibody fragment, such as a single-chain antibody. These
reagents are called immunotoxins. ... Cited by 133 - Related articles - BL Direct - All 4 versions
UK Hanisch, R Quirion - Brain Research Reviews, 1995 - Elsevier Interleukin-2 (IL-2), the cytokine also known as T-cell growth factor, has multiple immunoregulatory
functions and biological properties not only related to T-cells. In the past decade, substantial
evidence accumulated to suggest ... Cited by 115 - Related articles - All 7 versions
Y Reiter, U Brinkmann, B Lee, I Pastan - Nature biotechnology, 1996 - nature.com Disulfide-stabilized Fv fragments of antibodies (dsFv) are molecules in which the V H -V L
heterodimer is stabilized by an interchain disulfide bond engineered between structurally conserved
framework positions distant from ... Cited by 97 - Related articles - BL Direct - All 4 versions
- ►hematologylibrary.org [PDF] DC Matthews, FR Appelbaum, JF Eary, DR … - …, 1995 - bloodjournal.hematologylibrary.org . reserved Hematology; all rights Copyright 2007 by The American Society of Suite 200, Washington DC
20036. semimonthly by the American Society of Hematology, 1900 M St, NW, Blood (print ISSN
0006-4971, online ISSN 1528-0020), ... Cited by 87 - Related articles - BL Direct - All 4 versions
- ►hematologylibrary.org - Free from Publisher M Zhang, Z Yao, K Garmestani, DB Axworthy, … - …, 2002 - bloodjournal.hematologylibrary.org Leukemia generally provides better access than solid tumor to target antigens. This quality, along
with the inherent radiosensitivity of hematologic malignancies, has made clinical radioimmunotherapy
(RIT) of lymphomas one of the few ... Cited by 80 - Related articles - BL Direct - All 5 versions
