C Fiocchi - Gastroenterology, 1998 - Elsevier The field of gastroenterology offers many challenges to both the clinician and the
investigator, but few are as complex and enigmatic as inflammatory bowel disease (IBD). Crohn's
disease (CD) and ulcerative colitis (UC) have been known for well over one half a ... Cited by 1364 - Related articles - BL Direct - All 10 versions
JC Pickup, MA Crook - Diabetologia, 1998 - Springer The cause of the common type of Type II (non-insu- lin-dependent) diabetes mellitus, which affects
at least 100 million people throughout the world, is not known. One of the foremost challenges
we face is to account mechanistically for not only the defin- ing hyperglycaemia but also ... Cited by 602 - Related articles - BL Direct - All 3 versions
- ►annals.org DT Boumpas, GP Chrousos, RL Wilder, TR … - Annals of internal …, 1993 - Am Coll Physicians Glucocorticoids are pleiotropic hormones that at pharmacologic doses prevent or suppress inflammation
and other immunologically mediated processes. At the molecular level, glucocorticoids form
complexes with specific receptors that migrate to the nucleus where they interact with ... Cited by 437 - Related articles - All 5 versions
S Reichlin - New England Journal of Medicine, 1993 - content.nejm.org The long-held view that homeostatic mechanisms are integrated by the nervous and endocrine
systems has recently been expanded by information that these systems interact with the immune
system. Immune responses alter neural and endocrine function, and in turn, neural and ... Cited by 407 - Related articles - All 4 versions
RL Wilder - Annual review of immunology, 1995 - Annual Reviews The concept of an integrated bidirectionally regulated neuroendocrine-immune adaptive response
to stress has strong experimental support. The quality and inн tensity of this coordinated response
to stress varies depending upon age, gender, reproductive status, and other genetically ... Cited by 359 - Related articles - BL Direct - All 6 versions
JC Pickup - Diabetes care, 2004 - Am Diabetes Assoc There is increasing evidence that an ongoing cytokine-induced acute-phase response (sometimes
called low-grade inflammation, but part of a widespread activation of the innate immune
system) is closely involved in the pathogenesis of type 2 diabetes and associated ... Cited by 365 - Related articles - BL Direct - All 8 versions
JK Kiecolt-Glaser, L McGuire, TF Robles, R … - Annual review of …, 2002 - Annual Reviews ▪ Abstract Negative emotions can intensify a variety of health threats. We provide a broad framework
relating negative emotions to a range of diseases whose onset and course may be influenced
by the immune system; inflammation has been linked to a spectrum of conditions ... Cited by 357 - Related articles - BL Direct - All 7 versions
- ►tamu.edu [PDF] BS McEwen, CA Biron, KW Brunson, K Bulloch, WH … - Brain Research Reviews, 1997 - Elsevier Glucocorticoids are powerful regulators of immune function. Their role in reducing inflammation
and autoimmune responses is well known, as is their ability to induce apoptosis in immature
thymocytes. However, much of the story of glucocorticoid effects on immunity has been ... Cited by 355 - Related articles - BL Direct - All 6 versions
PG Popovich, P Wei, BT Stokes… - The Journal of Comparative …, 1997 - interscience.wiley.com The distribution of microglia, macrophages, T-lymphocytes, and astrocytes was characterized
throughout a spinal contusion lesion in Sprague-Dawley and Lewis rats by using
immunohistochemistry. The morphology, spatial localization, and activation state of these ... Cited by 331 - Related articles - All 5 versions
PS Aisen, KL Davis - American Journal of Psychiatry, 1994 - Am Psychiatric Assoc Page 1. Special Articles Am J Psychiatry 1 51 :8, August 1994 1105 Inflammatory
Mechanisms in Alzheimer's Disease: Implications for Therapy Paul S. Aisen, MD,
and Kenneth L. Davis, MD Objective: The purpose of this article ... Cited by 258 - Related articles - BL Direct - All 4 versions
