- ►unife.it [PDF] RS Hotchkiss, IE Karl - The New England journal of medicine, 2003 - nejm.highwire.org Sepsis is the leading cause of death in critically ill patients in the United
States. Sepsis develops in 750,000 people annually, and more than 210,000 of
them die. 1 , 2 After numerous unsuccessful trials of antiinflammatory ... Cited by 1613 - Related articles - BL Direct - All 39 versions
C Brun-Buisson, F Doyon, J Carlet, P … - Jama, 1995 - Am Med Assoc OBJECTIVE--To examine the incidence, risk factors, and outcome of severe sepsis
in intensive care unit (ICU) patients. DESIGN AND SETTING--Inception cohort
study from a 2-month prospective survey of 11,828 consecutive admissions to ... Cited by 781 - Related articles - BL Direct - All 4 versions
- ►critcaremed.org PE Bollaert, C Charpentier, B Levy, M … - Critical care medicine, 1998 - journals.lww.com From the Medical Intensive Care Unit (Drs. Bollaert, Levy, and Larcan), the
Surgical Intensive Care Unit (Drs. Charpentier and Audibert), and the Department
of Neurosciences (Dr. Debouverie), Hopital Central, Centre Hospitalier ... Cited by 761 - Related articles - BL Direct - All 9 versions
- ►physiology.org DR Meldrum - … Journal of Physiology- Regulatory, Integrative and …, 1998 - Am Physiological Soc The heart is a tumor necrosis factor (TNF)-producing organ. Both myocardial
macrophages and cardiac myocytes themselves synthesize TNF. Accumulating
evidence indicates that myocardial TNF is an autocrine contributor to ... Cited by 699 - Related articles - BL Direct - All 4 versions
WD Döcke, F Randow, U Syrbe, D Krausch, K … - Nature medicine, 1997 - nature.com Neutralization of proinflammatory cytokines, such as tumor necrosis factor-
(TNF- ) or interleukin-1 (IL-1), decreases mortality in several animal models of
sepsis. However, recent clinical trials did not show an unequivocal ... Cited by 620 - Related articles - BL Direct - All 4 versions
- ►chestpubs.org CL Holmes, BM Patel, JA Russell, KR Walley - Chest, 2001 - chestjournal.chestpubs.org Vasopressin is emerging as a rational therapy for the hemodynamic support of
septic shock and vasodilatory shock due to systemic inflammatory response
syndrome. The goal of this review is to understand the physiology of ... Cited by 391 - Related articles - BL Direct - All 7 versions
- ►uniroma1.it [PDF] C Alexander, ET Rietschel - Journal of Endotoxin Research, 2001 - ini.sagepub.com More than a century ago, Richard Pfeiffer (1858–1910), a collaborator of
Robert Koch at the Institute for Infectious Diseases in Berlin (Germany)
discovered that lysates of heat-killed bacteria of the cholera-inducing Cited by 308 - Related articles - BL Direct - All 4 versions
PE Marik, M Mohedin - JAMA-Journal of the American Medical Association-US …, 1994 - srlf.org Preliminary Communication The Contrasting Effects of Dopamine and Norepinephrine
on Systemic and Splanchnic Oxygen Utilization in Hyperdynamic Sepsis Paul E.
Marik, MBBCh. FC PSA, FRCPC. Mohammed Mohedin, MD Objective.—To compare ... Cited by 308 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org RS Hotchkiss, KW Tinsley, PE Swanson, RE … - The Journal of Immunology, 2001 - Am Assoc Immnol Patients with sepsis have impaired host defenses that contribute to the
lethality of the disorder. Recent work implicates lymphocyte apoptosis as a
potential factor in the immunosuppression of sepsis. If lymphocyte ... Cited by 300 - Related articles - BL Direct - All 3 versions
- ►ig.com.br [PDF] PM Honore, J Jamez, M Wauthier, PA Lee, T … - Critical care medicine, 2000 - journals.lww.com Objective: To evaluate the effects of short-term, high-volume hemofiltration
(STHVH) on hemodynamic and metabolic status and 28-day survival in patients with
refractory septic shock. Design: Prospective, interventional. Setting: ... Cited by 247 - Related articles - BL Direct - All 5 versions
