- ►shouxi.net JR O'Dell - New England Journal of Medicine, 2004 - content.nejm.org The diagnosis cannot be established by a single laboratory test or procedure but
is aided by the use of seven diagnostic criteria 16 that favor clinical factors
and, therefore, depend on the clinician's asking insightful questions and ... Cited by 291 - Related articles - BL Direct - All 17 versions
P Emery, FC Breedveld, EM Lemmel, JP … - Rheumatology, 2000 - Br Soc Rheumatology Results. After 1 yr, the mean changes in the leflunomide and methotrexate
groups, respectively, were -8.3 and -9.7 for tender joint count; -6.8 and -9.0
for swollen joint count; -0.9 and -1.2 for physician global assessment; ... Cited by 257 - Related articles - BL Direct - All 5 versions
- ►annals.org [PDF] JM Kremer - Annals of internal medicine, 2001 - Am Coll Physicians Because of radiographic evidence of progressive bone loss and the inability to
eliminate synovial proliferation with methotrexate, it became apparent that
therapy for rheumatoid arthritis needed further advancement. Methotrexate ... Cited by 156 - Related articles - BL Direct - All 9 versions
AE Van Ede, RF Laan, MJ Rood, TW Huizinga … - Arthritis Care & Research - interscience.wiley.com Patients with active RA (n = 434) were randomly assigned to receive MTX plus
either placebo, folic acid (1 mg/day), or folinic acid (2.5 mg/week). The
initial MTX dosage was 7.5 mg/week; dosage increases were allowed up to a ... Cited by 154 - Related articles - BL Direct - All 6 versions
- ►bmj.com CJ Haagsma, HJ Blom, PLCM van Riel, MA van … - British Medical Journal, 1999 - ard.bmj.com The pharmacotherapy of rheumatoid arthritis (RA) consists of first line agents
(non-steroidal anti-inflammatory drugs) and second line agents, also referred to
as disease modifying anti-rheumatic drugs. The latter drugs generally have ... Cited by 148 - Related articles - BL Direct - All 7 versions
- ►annals.org GS Alarcon, JM Kremer, M Macaluso, ME … - Annals of internal medicine, 1997 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg
Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this? ...
Background: Toxicity limits the use of methotrexate. Cited by 116 - Related articles - BL Direct - All 7 versions
- ►oxfordjournals.org S Hernandez-Diaz, MM Werler, AM Walker, AA … - American journal of epidemiology, 2001 - Oxford Univ Press Periconceptional folic acid supplementation reduces the risk of neural tube
defects (NTDs). To determine whether periconceptional exposure to folic acid
antagonists (FAAs) might therefore increase the risk of NTDs, the authors ... Cited by 116 - Related articles - BL Direct - All 9 versions
BN Cronstein - Rheumatic Disease Clinics of North America, 1997 - Elsevier Low-dose, weekly methotrexate is now standard second-line therapy for rheumatoid
arthritis. Methotrexate is the single agent to which new agents or combinations
of agents have been compared in efficacy studies, and methotrexate is ... Cited by 114 - Related articles - BL Direct - All 10 versions
- ►bmj.com M Cutolo, A Sulli, C Pizzorni, B Seriolo, RH … - British Medical Journal, 2001 - ard.bmj.com Figure 1 Adenosine increase by MTX and subsequent immunosuppression through
adenosine receptors. (A) MTX inhibits both, conversion of GAR FGAR and AICAR
FAICAR. However, inhibition of the second step is stronger, which results ... Cited by 111 - Related articles - BL Direct - All 6 versions
NRC Campbell - Archives of Internal Medicine, 1996 - archinte.highwire.org A marked reduction in the incidence ofneu¬ ral tube defects is seen in the
children of women who ingested supplements con¬ taining folie acid before and
after becom¬ ing pregnant.1'6To ensure the periconcep¬ tual use of folie ... Cited by 98 - Related articles - BL Direct - All 5 versions
