GL Davis, R Esteban-Mur, V Rustgi, J Hoefs, … - The New England journal of medicine, 1998 - nejm.highwire.org Results At the completion of treatment, serum levels of hepatitis C virus (HCV)
RNA were undetectable in 141 of the 173 patients who were treated with
interferon and ribavirin and in 80 of the 172 patients who were treated ... Cited by 997 - Related articles - BL Direct - All 6 versions
P Marcellin, N Boyer, A Gervais, M Martinot, … - Annals of internal medicine, 1997 - Am Coll Physicians Background: Less than 20% of patients with chronic hepatitis C have a sustained
response to interferon-α therapy. The long-term benefit of interferon-α with
regard to hepatic viral clearance and histologic improvement remains unknown. Cited by 417 - Related articles - BL Direct - All 5 versions
WG Bennett, Y Inoue, JR Beck, JB Wong, SG … - Annals of internal medicine, 1997 - Am Coll Physicians For author affiliations and current author addresses, see end of text. From the
University of Florida College of Medicine, Gainesville, Florida; Baylor College
of Medicine, Houston, Texas; Yamaguchi University School of Medicine, Ube, ... Cited by 220 - Related articles - BL Direct - All 6 versions
DTY Lau, DE Kleiner, MG Ghany, Y Park, P … - Hepatology, 1998 - interscience.wiley.com Sustained responses to interferon- occur in 10% to 25% of patients with chronic
hepatitis C, but the long-term outcome is not well defined. We evaluated the
long-term clinical, histological, and virological outcomes of 10 patients ... Cited by 211 - Related articles - BL Direct - All 3 versions
V Soriano, R Bravo, A Castro, J Castilla, P … - Clinical Infectious Diseases, 1996 - jstor.org V. Soriano, J. Garcia-Samaniego, R. Bravo, J. Gonzalez, A. Castro, J. Castilla,
P. Martinez-Odriozola, M. Colmenero, E. Carballo, D. Suarez, FJ
Rodriguez-Pifiero, A. Moreno, J. del Romero, J. Pedreira, J. ... Cited by 160 - Related articles - BL Direct - All 4 versions
KL Lindsay, GL Davis, ER Schiff, HC … - Hepatology, 1996 - interscience.wiley.com To evaluate response rates to 3, 5, or 10 million units (MU) of interferon
alfa-2b, given thrice weekly, and to determine whether higher doses of
interferon increase the likelihood or durability of the response, a ... Cited by 111 - Related articles - BL Direct - All 3 versions
C Cammā, V Di Marco, O Lo Iacono, P Almasio, … - Journal of hepatology, 1998 - Elsevier Results: Sixty-two patients (15.1%: 54 with chronic hepatitis, eight with
cirrhosis) were sustained responders. At the end of follow-up, 56 out of 62
sustained responders (90.3%) were serum HCV RNA negative. No biochemical ... Cited by 85 - Related articles - BL Direct - All 6 versions
H Tanaka, H Tsukuma, A Kasahara, N Hayashi … - International Journal of Cancer, 2000 - interscience.wiley.com The effect of interferon on the long-term clinical outcome of patients with
chronic hepatitis C remains unclear. This study included 594 patients with
chronic hepatitis C who received interferon- therapy (Interferon group) and ... Cited by 67 - Related articles - BL Direct - All 4 versions
J McHutchison, T Poynard, R Esteban-Mur, GL … - Hepatology, 2002 - interscience.wiley.com The clinical use of measuring hepatic hepatitis C virus (HCV) RNA before and
after therapy in patients with chronic hepatitis C has been assessed in a number
of small clinical trials. Viral clearance from the liver may be a better ... Cited by 63 - Related articles - BL Direct - All 5 versions
PA Bonis, JP Ioannidis, JC Cappelleri, MM … - Hepatology, 1997 - interscience.wiley.com The current goal of interferon treatment for chronic hepatitis C is to normalize
alanine aminotransferase (ALT) and to eradicate detectable viral RNA. Many
patients do not achieve this objective during treatment, and most do not ... Cited by 56 - Related articles - BL Direct - All 3 versions
