- ►direct-ms.org [PDF] A Davidson, B Diamond - New England Journal of Medicine, 2001 - content.nejm.org Autoimmune diseases, with the exception of rheumatoid arthritis and autoimmune
thyroiditis, are individually rare, but together they affect approximately 5
percent of the population in Western countries. 1 , 2 They are a ... Cited by 446 - Related articles - All 13 versions
- ►nih.gov [PDF] JE Salmon, S Millard, LA Schachter, FC … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov Allelic variants of Fc R confer distinct phagocytic capaci- ties providing a
mechanism for heritable susceptibility to immune complex disease. Human Fc RIIa
has two codomi- nantly expressed alleles, R131 and H131, which differ sub- ... Cited by 320 - Related articles - All 7 versions
- ►nih.gov D Jawaheer, MF Seldin, CI Amos, WV Chen, R … - The American Journal of Human Genetics, 2001 - Elsevier Rheumatoid arthritis (RA) is an autoimmune/inflammatory disorder with a complex
genetic component. We report the first major genomewide screen of multiplex
families with RA gathered in the United States. The North American ... Cited by 288 - Related articles - BL Direct - All 11 versions
- ►nih.gov D Jawaheer, W Li, RR Graham, W Chen, A Damle … - The American Journal of Human Genetics, 2002 - Elsevier Rheumatoid arthritis (RA) is an inflammatory disease with a complex genetic
component. An association between RA and the human leukocyte antigen (HLA)
complex has long been observed in many different populations, and most ... Cited by 118 - Related articles - BL Direct - All 18 versions
J Vinasco, Y Beraun, A Nieto, A Fraile, L … - Tissue Antigens, 1997 - interscience.wiley.com The purpose of this work was to analyze the possible influence of TNF loci
polymorphism on the susceptibility and/or the disease profile of rheumatoid
arthritis (RA). Tumor necrosis factor (α and β) genotypes were determined ... Cited by 100 - Related articles - BL Direct - All 3 versions
R Lavizzo-Mourey, ER Mackenzie - Annals of Internal Medicine, 1996 - Am Coll Physicians We are currently witnessing a radical change in the health care system in the
United States as a result of the managed care juggernaut. Driven by the
imperative to stem increasing health care costs, managed care seeks to save ... Cited by 92 - Related articles - BL Direct - All 5 versions
- ►nih.gov K Okamoto, S Makino, Y Yoshikawa, A Takaki, … - The American Journal of Human Genetics, 2003 - Elsevier Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with a complex
etiology in which environmental factors within a genetically susceptible host
maneuver the innate and adaptive arms of the immune system toward ... Cited by 90 - Related articles - BL Direct - All 5 versions
HS El-Gabalawy, R Goldbach-Mansky, D Smith … - Arthritis Care & Research - interscience.wiley.com The HLA alleles A, B, C, DR 1, and DQ 1 were determined in a cohort of 211
patients (mean age 42 years, 64% female, 79% white) with recent-onset synovitis
in 1 or more peripheral joints. At a mean disease duration of 33 weeks, 98 ... Cited by 69 - Related articles - BL Direct - All 3 versions
JD Gorman, RF Lum, JJ Chen, ME Suarez- … - Arthritis Care & Research - interscience.wiley.com The strongest known genetic association in rheumatoid arthritis (RA) is with
HLA-DRB1 alleles that share a similar amino acid sequence, termed the shared
epitope (SE). Although many studies have examined the association of the SE ... Cited by 69 - Related articles - BL Direct - All 3 versions
CM Weyand, PA Klimiuk, JJ Goronzy - Springer seminars in immunopathology, 1998 - Springer Abstract. Rheumatoid arthritis (RA) is now recognized as a multigene disorder
with a number of genetic polymorphisms contributing to disease pathogenesis.
Here, we pro- pose that the diagnostic category of RA includes multiple ... Cited by 62 - Related articles - BL Direct - All 4 versions
