R Fass, B Naliboff, L Higa, C Johnson, A Kodner, J … - Gastroenterology, 1998 - Elsevier Chronic retrosternal pain associated with reflux of gastric contents into the esophagus is the
hallmark of gastroesophageal reflux disease (GERD). Sensitization of esophageal chemoreceptors
either directly by intermittent exposure to refluxed acid or indirectly through esophagitis- ... Cited by 182 - Related articles - BL Direct - All 7 versions
- ►bmj.com RE Clouse, JE Richter, RC Heading, J Janssens, … - British Medical …, 1999 - gut.bmj.com Functional esophageal disorders represent chronic symptoms that typify esophageal disease
yet have no identifiable structural or metabolic basis (table 1). Mechanisms responsible for the
symptoms are poorly understood, but a combination of physiologic and psychosocial ... Cited by 140 - Related articles - BL Direct - All 11 versions
- ►opticalportal.com [PDF] JP Galmiche, RE Clouse, A Bálint, IJ Cook, PJ Kahrilas, … - Gastroenterology, 2006 - Elsevier Functional esophageal disorders represent processes accompanied by typical esophageal symptoms
(heartburn, chest pain, dysphagia, globus) that are not explained by structural disorders,
histopathology-based motor disturbances, or gastroesophageal reflux disease. ... Cited by 115 - Related articles - All 29 versions
- ►bmj.com JE Kellow, M Delvaux, F Azpiroz, M Camilleri, EMM … - British Medical …, 1999 - gut.bmj.com Figure 1 Extrinsic and intrinsic control of gastrointestinal motility. The extrinsic sympathetic and
parasympathetic supply to the gut modulates the function of the enteric brain located in ganglionated
plexi along the gastrointestinal tract. Transmitters released from the enteric neurons, ... Cited by 109 - Related articles - BL Direct - All 9 versions
DH Balaban, Y Yamamoto, J Liu, N Pehlivanov, R … - Gastroenterology, 1999 - Elsevier In 1786, Heberden presented the classical account of angina as chest pain brought on by exertion
and relieved by rest. 1 Most patients presenting with this symptom have coronary artery
disease. However, up to 30% of patients undergoing cardiac catheterization for ... Cited by 107 - Related articles - BL Direct - All 7 versions
S Rodriguez-Stanley, M Robinson, DL Earnest, B … - The American journal of …, 1999 - nature.com Little is known about esophageal nociceptive thresholds in chronic heartburn sufferers with normal
clinical findings. The aim of this study was to evaluate and to characterize the pathogenesis of
heartburn in subjects who chronically use antacids and had not sought medical attention. Cited by 87 - Related articles - BL Direct - All 6 versions
- ►bmj.com PL Peghini, PO Katz, DO Castell - British Medical Journal, 1998 - gut.bmj.com EXPERIMENTAL PROTOCOL The effect of imipramine on oesophageal sensory perception
was assessed in a randomised, double blind, placebo controlled, crossover trial. Subjects were
randomised by blindly taking a number from a closed container and given identical ... Cited by 72 - Related articles - BL Direct - All 7 versions
JE Pandolfino, PJ Kahrilas - Gastroenterology, 2005 - Elsevier The utility of esophageal manometry in clinical practice resides in 3 domains: (1) to accurately
define esophageal motor function, (2) to define abnormal motor function, and (3) to delineate
a treatment plan based on motor abnormalities. Since the first American ... Cited by 73 - Related articles - All 15 versions
F De Ponti, JR Malagelada - Pharmacology and Therapeutics, 1998 - Elsevier Functional gut disorders include several clinical entities defined on the basis of symptom patterns
(eg, functional dyspepsia, irritable bowel syndrome, functional abdominal pain, functional abdominal
bloating), for which there is no established pathophysiological mechanism. Because ... Cited by 69 - Related articles - BL Direct - All 4 versions
J Fang, D Bjorkman - The American journal of gastroenterology, 2001 - nature.com Approximately 30% of coronary angiograms performed in this country are negative for significant
coronary artery disease. These patients are classified as having noncardiac or unexplained chest
pain (UCP). Despite the good overall prognosis, this condition has significant morbidity ... Cited by 64 - Related articles - BL Direct - All 5 versions
