D Raoult, ML Birg, BL Scola, PE Fournier, M … - The New England journal of medicine, 2000 - nejm.highwire.org Results The bacterium of Whipple's disease was grown successfully in HEL cells,
and we established subcultures of the isolate. Indirect immunofluorescence
assays showed that the patient's serum reacted specifically against the ... Cited by 227 - Related articles - BL Direct - All 6 versions
YW Tang, GW Procop, DH Persing - Clinical Chemistry, 1997 - Am Assoc Clin Chem Over the past several years, the development and application of molecular
diagnostic techniques has initiated a revolution in the diagnosis and monitoring
of infectious diseases. Microbial phenotypic characteristics, such as ... Cited by 137 - Related articles - BL Direct - All 5 versions
T Marth, D Raoult - The Lancet, 2003 - Elsevier Whipple's disease, or intestinal lipodystrophy, is a systemic infectious
disorder affecting mostly middle-aged white men. Patients present with weight
loss, arthralgia, diarrhoea, and abdominal pain. The disease is commonly ... Cited by 128 - Related articles - BL Direct - All 14 versions
DN Fredricks, DA Relman - Clinical Infectious Diseases, 1999 - jstor.org Application of Polymerase Chain Reaction to the Diagnosis of Infectious Diseases ... David N. Fredricks and David A. Relman ... From the Division of Infectious
Diseases, Department of Medicine and Department of Microbiology and ... Cited by 115 - Related articles - All 3 versions
- ►nih.gov F Fenollar, D Raoult - Current Gastroenterology Reports, 2003 - Springer Introduction Whipple's disease, first described in 1907 by GH Whipple, is a rare
chronic infectious disease that is fatal in the absence of adequate treatment
[1]. The disorder is caused by a bacterium, Tropheryma whipplei [2–6]. It ... Cited by 113 - Related articles - BL Direct - All 19 versions
- ►nih.gov F Dutly, M Altwegg - Clinical Microbiology Reviews, 2001 - Am Soc Microbiol Whipple's disease is a rare bacterial infection that may involve any organ
system in the body. It occurs primarily in Caucasian males older than 40 years.
The gastrointestinal tract is the most frequently involved organ, with ... Cited by 101 - Related articles - BL Direct - All 8 versions
HU Ehrbar, P Bauerfeind, F Dutly, HR Koelz, … - The Lancet, 1999 - Elsevier We investigated 105 patients (60 men, aged 20-80 years) referred for elective
gastroscopy without clinical signs of Whipple's disease. The study was approved
by the ethics committee of the University of Zurich, and informed consent ... Cited by 99 - Related articles - BL Direct - All 7 versions
S Street, HD Donoghue, GH Neild - The Lancet, 1999 - Elsevier Tropheryma whippelii is the putative pathogen in Whipple's disease. It has not
been cultured, but has been propagated in deactivated macrophages. On the basis
of its 16S ribosomal RNA (rRNA) gene sequence, it is related to the group B ... Cited by 94 - Related articles - BL Direct - All 5 versions
- ►sgmjournals.org [PDF] B La Scola, F Fenollar, PE Fournier, M … - International Journal of Systematic and Evolutionary …, 2001 - Soc General Microbiol 1 Unite des Rickettsies, Universite de la Me!diterrane!e, Faculte! de Me!decine,
CNRS UPRESA 6020, 27 Boulevard Jean Moulin, 13385 Marseille, France 2 Department
of Medical Microbiology, University of Zu$rich, Gloriastrasse 30, 8028 ... Cited by 85 - Related articles - BL Direct - All 5 versions
- ►zhaoys.com [PDF] D Raoult, B La Scola, P Lecocq, H Lepidi, PE … - Jama, 2001 - Am Med Assoc Context Culture of Tropheryma whippelii has been established only once, in human
fibroblast cell lines from a heart valve inoculum. Molecular-based diagnostic
techniques, although highly sensitive, may be less specific. New diagnostic ... Cited by 58 - Related articles - BL Direct - All 6 versions
