PM Ridker, JP Miletich, CH Hennekens, JE … - Jama, 1997 - Am Med Assoc OBJECTIVE: To estimate ethnic-specific prevalence rates of factor V Leiden, an
inherited defect of hemostasis associated with risk of venous thrombosis.
DESIGN: Survey of 4047 American men and women participating in the ... Cited by 391 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org FA Anderson Jr, FA Spencer - Circulation, 2003 - Am Heart Assoc Until the 1990s, venous thromboembolism (VTE) was viewed primarily as a
complication of hospitalization for major surgery (or associated with the late
stage of terminal illness). However, recent trials in patients hospitalized ... Cited by 351 - Related articles - BL Direct - All 11 versions
DT Price, PM Ridker - Annals of Internal Medicine, 1997 - Am Coll Physicians Background: A single point mutation in the gene coding for coagulation factor V
results in a form of factor Va that is resistant to degradation by activated
protein C and leads to a relative hypercoagulable state. This mutation, ... Cited by 241 - Related articles - BL Direct - All 7 versions
- ►annals.org PM Ridker, JP Miletich, JE Buring, AA Ariyo, … - Annals of internal medicine, 1998 - Am Coll Physicians Add to CiteULike Add to Complore Add to Connotea Add to Del.icio.us Add to Digg
Add to Facebook Add to Reddit Add to Technorati Add to Twitter What's this? ...
Background: Recurrent pregnancy loss may result from hypercoagulability. Cited by 160 - Related articles - BL Direct - All 6 versions
WW Grody, JH Griffin, AK Taylor, BR Korf, JA … - Genetics in Medicine, 2001 - journals.lww.com Recommendation 1 When appropriate clinical care requires testing for the factor
V Leiden allele, either direct DNA-based genotyping or a factor V
Leiden-specific functional assay is recommended. Patients who test positive ... Cited by 130 - Related articles - BL Direct - All 4 versions
- ►annals.org [PDF] S Middeldorp, JR Meinardi, MMW Koopman, E … - Annals of internal medicine, 2001 - Am Coll Physicians Background: The factor V Leiden mutation is a common genetic defect associated
with an increased risk for venous thromboem- bolism. The clinical implications
for asymptomatic carriers of this mutation and, consequently, the ... Cited by 121 - Related articles - All 11 versions
- ►ahajournals.org DM Herrington, E Vittinghoff, TD Howard, DA … - Arteriosclerosis, thrombosis, and vascular biology, 2002 - Am Heart Assoc Abstract— Oral contraceptive use in women with factor V Leiden is associated
with increased rates of venous thromboembolic events (VTEs). However, the
effects of hormone replacement therapy (HRT) in postmenopausal women with ... Cited by 123 - Related articles - BL Direct - All 9 versions
- ►haematologica.com [PDF] V De Stefano, E Rossi, K Paciaroni, G Leone - Haematologica, 2002 - haematologica.org State of the Art. The associated risk for VTE is different according to
genotype, being higher among the carriers of natural anticoagulant deficiencies
and homozygotes for factor V Leiden. The overall prevalence of throm- ... Cited by 103 - Related articles - BL Direct - All 15 versions
RD Press, KA Bauer, JL Kujovich, JA Heit - Archives of Pathology and Laboratory Medicine, 2002 - arpa.allenpress.com Conclusions.—Consensus recommendations were generated for topics of direct
clinical relevance, including (1) defining those patients (and family members)
who should (and should not) be tested for FVL; (2) defining the preferred ... Cited by 91 - Related articles - BL Direct - All 4 versions
- ►nih.gov Q Yang, MJ Khoury, L Botto, JM Friedman, … - The American Journal of Human Genetics, 2003 - Elsevier Studies have argued that genetic testing will provide limited information for
predicting the probability of common diseases, because of the incomplete
penetrance of genotypes and the low magnitude of associated risks for the ... Cited by 91 - Related articles - BL Direct - All 10 versions
