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Scholar Results 1 - 10 of about 114 citing Strober: The pathogenesis of mucosal inflammation in murine models of inflammatory bowel.... (0.09 sec) 

IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: …

- jimmunol.org
TT Pizarro, MH Michie, M Bentz, J … - The Journal of …, 1999 - Am Assoc Immnol
IL-18, a novel immunoregulatory cytokine with potent IFN- -inducing activities, may play an important
role in Th1-mediated chronic inflammatory disorders. The aim of the present study was to characterize
the expression and localization of IL-18 in colonic specimens and isolated mucosal cell ...
Cited by 323 - Related articles - BL Direct - All 6 versions

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

- cell.com
A Laurence, CM Tato, TS Davidson, Y Kanno, Z Chen, … - Immunity, 2007 - Elsevier
Recent work has identified a new subset of effector T cells that produces interleukin (IL)-17 known
as T helper 17 (Th17) cells, which is involved in the pathophysiology of inflammatory diseases
and is thought to be developmentally related to regulatory T (Treg) cells. Because of its ...
Cited by 251 - Related articles - All 8 versions

[PDF] Selected loss of tolerance evidenced by Crohn's disease–associated immune …


CJ Landers, O Cohavy, R Misra, H Yang, YC … - …, 2002 - pathnet.medsch.ucla.edu
Background & Aims: Previous studies in Crohn's disease suggest global loss of tolerance with
sonicated bacteria preparations containing hundreds of antigens. Monoasso- ciation studies
show that a solitary bacterium can induce colitis in one animal model, whereas another is ...
Cited by 199 - Related articles - BL Direct - All 13 versions

Cytokines and transcription factors that regulate T helper cell differentiation: new …

- laurentienne.ca [PDF] 
D Agnello, CSR Lankford, J Bream, A Morinobu, M … - Journal of Clinical …, 2003 - Springer
Journal of Clinical Immunology, Vol. 23, No. 3, May 2003 (C 2003) ... Cytokines and Transcription
Factors That Regulate T Helper ... Cell Differentiation: New Players and New Insights ... DAVIDE
AGNELLO,1 CARLA SR LANKFORD,2 JAY BREAM,1 AKIO MORINOBU,1 MASSIMO ...
Cited by 187 - Related articles - BL Direct - All 67 versions

Clinical aspects and pathophysiology of inflammatory bowel disease

- nih.gov
BA Hendrickson, R Gokhale, JH Cho - Clinical microbiology reviews, 2002 - Am Soc Microbiol
The chronic inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are recognized
as important causes of gastrointestinal disease in children and adults. In this review we delineate
the clinical manifestations and diagnostic features of IBD. In addition, we summarize ...
Cited by 145 - Related articles - BL Direct - All 8 versions

A preliminary study of growth hormone therapy for Crohn's disease


AE Slonim, L Bulone, MB Damore, T … - The New England …, 2000 - nejm.highwire.org
A PRELIMINARY STUDY OF GROWTH HORMONE THERAPY FOR CROHN'S DISEASE ...
A PRELIMINARY STUDY OF GROWTH HORMONE THERAPY FOR CROHN'S DISEASE ...
A LFRED E. S LONIM , MD, L INDA B ULONE , RN, M ARY B. D AMORE , MD, T ERESIA ...
Cited by 139 - Related articles - BL Direct - All 5 versions

Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected …

- jimmunol.org
PG Andres, PL Beck, E Mizoguchi, A … - The Journal of …, 2000 - Am Assoc Immnol
The chemokine receptors CCR2 and CCR5 and their respective ligands regulate leukocyte chemotaxis
and activation. To determine the role of these chemokine receptors in the regulation of the intestinal
immune response, we induced colitis in CCR2- and CCR5-deficient mice by continuous ...
Cited by 134 - Related articles - BL Direct - All 4 versions

Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile …


B Egger, M Bajaj-Elliott, TT MacDonald, R Inglin, VE … - Digestion, 2000 - content.karger.com
Investigation of the pathogenesis and treatment of ulcerative colitis and Crohn's disease has
been of increasing interest over the last decade. However, the lack of an ideal animal model
mimicking the acute and chronic, spontaneously relapsing course of idiopathic ...
Cited by 128 - Related articles - BL Direct - All 6 versions

Treatment of experimental (trinitrobenzene sulfonic acid) colitis by intranasal …

- nih.gov
A Kitani, IJ Fuss, K Nakamura, OM Schwartz, T … - Journal of Experimental …, 2000 - jem.rupress.org
In this study, we show that a single intranasal dose of a plasmid encoding active transforming
growth factor ß1 (pCMV-TGF-ß1) prevents the development of T helper cell type 1 (Th1)-mediated
experimental colitis induced by the haptenating reagent, 2,4,6-trinitrobenzene sulfonic ...
Cited by 120 - Related articles - BL Direct - All 4 versions

Association between polymorphisms in the Toll-like receptor 4, CD14, and …


M Gazouli, G Mantzaris, A Kotsinas, P Zacharatos, E … - World J Gastroenterol, 2005 - wjgnet.com
Abstract AIM: Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases with
a significant genetic background. Apart from CARD15/NOD2 gene, evidence is accumulating
that molecules related to the innate immune response such as CD14 or Toll-like receptor ...
Cited by 112 - Related articles - Cached - All 8 versions


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