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Scholar Results 1 - 10 of about 40 citing Wee: Risk for valvular heart disease among users of fenfluramine and dexfenfluramine who.... (0.16 sec) 

Evidence for possible involvement of 5-HT2B receptors in the cardiac valvulopathy …

- ahajournals.org
RB Rothman, MH Baumann, JE Savage, L … - Circulation, 2000 - Am Heart Assoc
Methods and Results—Medications known or suspected to cause VHD (positive
controls) and medications not associated with VHD (negative controls) were
screened for activity at 11 cloned serotonin receptor subtypes by use of ...
Cited by 215 - Related articles - BL Direct - All 6 versions

Accelerated communication: possible role of valvular serotonin 5-HT2B receptors in the …

- aspetjournals.org
LW Fitzgerald, TC Burn, BS Brown, JP … - Molecular Pharmacology, 2000 - ASPET
Dexfenfluramine was approved in the United States for long-term use as an
appetite suppressant until it was reported to be associated with valvular heart
disease. The valvular changes (myofibroblast proliferation) are ...
Cited by 177 - Related articles - All 6 versions

Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety


G Glazer - Archives of Internal Medicine, 2001 - Am Med Assoc
To clarify the efficacy of antiobesity drugs, this article reviews all long-term
( 36 weeks), placebo-controlled trials of obesity pharmacotherapy published
since 1960. Since fears of anorexiant-induced heart valve damage preclude ...
Cited by 109 - Related articles - BL Direct - All 6 versions

Pharmacological therapy of obesity: past, present, and future

- endojournals.org
DS Weigle - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
There is probably no medical condition for which a safe and effective form of
pharmacotherapy is more highly desired than obesity. Neither is there a
condition for which effective treatment would spare so much suffering for ...
Cited by 61 - Related articles - BL Direct - All 8 versions

Metastatic carcinoid tumors: a clinical review

- alphamedpress.org
JM Zuetenhorst, BG Taal - The Oncologist, 2005 - AlphaMed Press
The Oncologist ...
Cited by 58 - Related articles - All 11 versions

Prevalence and determinants of valvulopathy in patients treated with dexfenfluramine

- ahajournals.org
BK Shively, CA Roldan, EA Gill, T Najarian, … - Circulation, 1999 - Am Heart Assoc
Methods and Results—Echocardiography was performed on subjects recruited from
26 prescribing sites in 15 states. The total sample of 412 subjects included 172
dexfenfluramine patients and 172 unexposed controls matched for age, sex, ...
Cited by 53 - Related articles - BL Direct - All 6 versions

Carcinoid heart disease


JM Zuetenhorst, JMGM Bonfrer, CM Korse, R … - CA A Cancer Journal for Clinicians - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 44 - Related articles - BL Direct - All 4 versions

The progression of fenfluramine-associated valvular heart disease assessed by …

- annals.org [PDF] 
ST Mast, JG Jollis, T Ryan, KJ Anstrom, JL … - Annals of internal medicine, 2001 - Am Coll Physicians
Background: An association between the dietary suppressants fenfluramine and
dexfenfluramine and valvular heart disease was first described in patients from
North Dakota and Minnesota in 1997. Limited data are available on the ...
Cited by 46 - Related articles - BL Direct - All 8 versions

Safety of drug therapies used for weight loss and treatment of obesity


LL Ioannides-Demos, J Proietto, AM Tonkin, … - Drug safety, 2006 - ingentaconnect.com
Abstract. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . 277 1. Drug Therapy . . . . . . . . . . . . . . . . . . . . ...
Cited by 41 - Related articles - BL Direct - All 8 versions

[PDF] Long-term impairment of anterograde axonal transport along fiber projections originating in …


BT Callahan, BJ Cord, GA Ricaurte - Synapse, 2001 - research.lycaeum.org
ABSTRACT To further evaluate the serotonin (5-HT) neurotoxic potential of
substi- tuted amphetamines, we used tritiated proline to examine anterograde
transport along ascending axonal projections originating in the rostral ...
Cited by 36 - Related articles - View as HTML - BL Direct - All 7 versions


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