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Scholar Results 1 - 10 of about 202 citing Kullo: Vulnerable plaque: pathobiology and clinical implications. (0.09 sec) 

Noninvasive detection and evaluation of atherosclerotic coronary plaques with …

- onlinejacc.org
S Schroeder, AF Kopp, A Baumbach, C Meisner, A … - Journal of the American …, 2001 - Elsevier
The risk of acute coronary syndromes caused by plaque disruption and thrombosis depends
on plaque composition rather than stenosis severity. Thus, the reliable noninvasive assessment
of plaque configuration would constitute an important step forward for risk stratification in ...
Cited by 614 - Related articles - BL Direct - All 12 versions

Carotid atherosclerotic plaque: noninvasive MR characterization and identification …

- rsna.org
C Yuan, LM Mitsumori, KW Beach, KR Maravilla - Radiology, 2001 - radiology.rsna.org
Measurement of vessel stenosis by using ultrasonography or angiography remains the principal
method for determining the severity of carotid atherosclerosis and the need for
endarterectomy. The ipsilateral stroke rate, however—even in patients with severely ...
Cited by 258 - Related articles - BL Direct - All 5 versions

Overall cardiovascular profile of sildenafil citrate


RM Zusman, A Morales, DB Glasser, IH Osterloh - The American journal of …, 1999 - Elsevier
Sildenafil, a selective inhibitor of phosphodiesterase type 5 (PDE5), is the first in a new class
of orally effective treatments for erectile dysfunction. During sexual stimulation, the cavernous
nerves release nitric oxide (NO), which induces cyclic guanosine monophosphate ...
Cited by 249 - Related articles - BL Direct - All 4 versions

Atherothrombosis and high-risk plaque part I: evolving concepts

- onlinejacc.org
V Fuster, PR Moreno, ZA Fayad, R Corti, JJ … - Journal of the American …, 2005 - Elsevier
Atherothrombosis is a complex disease in which cholesterol deposition, inflammation, and thrombus
formation play a major role. Rupture of high-risk, vulnerable plaques is responsible for coronary
thrombosis, the main cause of unstable angina, acute myocardial infarction, and sudden ...
Cited by 257 - Related articles - BL Direct - All 18 versions

Mechanisms of plaque vulnerability and rupture

- onlinejacc.org
PK Shah - Journal of the American College of Cardiology, 2003 - Elsevier
Rupture of atherosclerotic plaque has been identified as the proximate event in the majority of
cases of acute ischemic syndromes. Plaque rupture exposes thrombogenic components of the
plaque, activating the clotting cascade and promoting thrombus formation. Future culprit ...
Cited by 240 - Related articles - BL Direct - All 11 versions

Thrombus formation on atherosclerotic plaques: pathogenesis and clinical …

- annals.org [PDF] 
U Rauch, JI Osende, V Fuster, JJ Badimon, … - Annals of internal …, 2001 - Am Coll Physicians
Purpose: To describe the characteristics of thrombus formation on atherosclerotic plaques, the
clinical expression of atherothrom- bosis in vascular disease, and some of the most recent therapeutic
approaches in cardiovascular disease. Data Sources: MEDLINE search for English- ...
Cited by 218 - Related articles - BL Direct - All 6 versions

In vivo imaging of proteolytic activity in atherosclerosis

- ahajournals.org
J Chen, CH Tung, U Mahmood, V Ntziachristos, R … - Circulation, 2002 - Am Heart Assoc
Methods and Results— Using western-type diet–fed apoE and apoE/endothelial NO synthase
double knockout mice as models of atherosclerosis, we show (1) that cathepsin B is upregulated
in atherosclerotic lesions characterized by high degrees of inflammation compared with ...
Cited by 195 - Related articles - BL Direct - All 5 versions

Stroke prevention therapy beyond antithrombotics: unifying mechanisms in …


PB Gorelick - Stroke, 2002 - Am Heart Assoc
Background— It is estimated that about half of cardiovascular disease risk is explained by conventional
risk factors. The realization that atherosclerosis is an inflammatory disease has led to a search
for new stroke and cardiovascular disease risk factors and treatments. As such, the ...
Cited by 195 - Related articles - BL Direct - All 9 versions

Left ventricular muscle mass and elevated heart rate are associated with coronary …

- ahajournals.org
UE Heidland, BE Strauer - Circulation, 2001 - Am Heart Assoc
Methods and Results— This study retrospectively analyzed 106 patients who underwent 2 coronary
angiography procedures within 6 months. We investigated 53 patients with initially smooth stenoses
who developed plaque disruption by the time of the second coronary angiogram and ...
Cited by 189 - Related articles - BL Direct - All 7 versions

Association of coronary heart disease risk factors with microscopic qualities of …

- ahajournals.org
HC McGill Jr, CA McMahan, AW Zieske, RE Tracy, GT … - Circulation, 2000 - Am Heart Assoc
Methods and Results—Histological sections of left anterior descending coronary arteries
(LADs) from 760 autopsied 15- to 34-year-old victims of accidents, homicides, and suicides were
graded according to the American Heart Association (AHA) system and computerized ...
Cited by 155 - Related articles - BL Direct - All 6 versions


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