- ►uab.edu [PDF] WM Lee - The New England journal of medicine, 2003 - nejm.highwire.org In the past five years, two drugs have been withdrawn from the market by the
Food and Drug Administration (FDA) for causing severe liver injury, a potential
danger that had not been fully recognized in the course of the preapproval ... Cited by 665 - Related articles - BL Direct - All 22 versions
JM Kent - The Lancet, 2000 - Elsevier A major goal of antidepressant development is to improve on preceding drug
classes with agents with greater specificity (and therefore fewer unwanted
side-effects) and with more rapid onset of antidepressant action. To this ... Cited by 195 - Related articles - BL Direct - All 4 versions
JH Lewis - Medical Clinics of North America, 2000 - Elsevier A temporal relationship usually is evident with an implicated drug, with most
cases of acute DILD occurring within 1 week to 3 months of exposure. A positive
response to discontinuing the agent (dechallenge) enhances the suspicion, ... Cited by 158 - Related articles - BL Direct - All 20 versions
AP Li - Chemico-biological interactions, 2002 - Elsevier Idiosyncratic drug toxicity is generally believed to be a phenomenon that cannot
be readily evaluated experimentally. Reasons for this difficulty include the
following: 1. It is a rare event (<1/5000) and therefore impossible to be ... Cited by 60 - Related articles - All 7 versions
K Selim, N Kaplowitz - Hepatology, 1999 - usagiedu.com Psychotropic drugs with hepatotoxic potential can be classified based on their
intended use: 1) antipsychotics- neuroleptics including phenothiazines,
butyrophenones, and clozapine; 2) antidepressants including tricyclics, ... Cited by 38 - Related articles - BL Direct - All 10 versions
C CRONE, GM GABRIEL - Journal of psychiatric Practice, 2003 - journals.lww.com Hepatitis C virus (HCV) is a ribonucleic acid (RNA) virus belonging to the
Flaviviridae family with a mono- typic genus of Hepacivirus. In contrast,
hepatitis A virus (HAV) is a RNA virus of the Picornavirus family and ... Cited by 32 - Related articles - BL Direct - All 3 versions
- ►aspetjournals.org AS Kalgutkar, ADN Vaz, ME Lame, KR Henne, … - Drug Metabolism and Disposition, 2005 - ASPET The therapeutic benefits of the antidepressant nefazodone have been hampered by
several cases of acute hepatotoxicity/liver failure. Although the mechanism of
hepatotoxicity remains unknown, it is possible that reactive metabolites of ... Cited by 32 - Related articles - All 4 versions
DE Stewart - Can J Psy chia try, 2002 - ww1.cpa-apc.org Limi ta tions • Ad verse drug re ac tions are un der re ported to the Ca na
dian Ad verse Drug Re ac tion Moni tor ing Pro gramme (CADRMP). • Cause and ef
fect re la tions have not been es tab lished for most ad verse drug re ... Cited by 34 - Related articles - View as HTML - BL Direct - All 10 versions
O Spigset, S Hägg, A Bate - International clinical psychopharmacology, 2003 - journals.lww.com Severe hepatic adverse drug reactions have been occa- sionally reported in the
literature for the selective serotonin reuptake inhibitors (SSRIs), venlafaxine
and nefazodone. In addition, a few case reports have suggested a possible ... Cited by 29 - Related articles - BL Direct - All 5 versions
