- ►ucsd.edu [PDF] RM Siegel, JK Frederiksen, DA Zacharias, FKM Chan, … - Science, 2000 - sciencemag.org A list of selected additional articles on the Science Web sites ... 285 article(s) on the ISI Web
of Science. cited by This article has been ... : subject collections This article appears in the following ... 2000 by the American Association for the Advancement of Science; all rights reserved. ... Cited by 389 - Related articles - BL Direct - All 13 versions
- ►nih.gov HY Chang, X Yang - Microbiology and molecular biology reviews, 2000 - Am Soc Microbiol Caspases are a large family of evolutionarily conserved proteases found from Caenorhabditis
elegans to humans. Although the first caspase was identified as a processing enzyme for
interleukin-1 , genetic and biochemical data have converged to reveal that many ... Cited by 348 - Related articles - BL Direct - All 7 versions
- ►nih.gov [PDF] TA Chatila, F Blaeser, N Ho, HM Lederman … - Journal of Clinical …, 2000 - Am Soc Clin Investig X-linked autoimmunity-allergic disregulation syndrome (XLAAD) is an X-linked recessive immunological
disorder characterized by multisystem autoimmunity, particularly early-onset type 1 diabetes
mellitus, associated with manifestations of severe atopy including eczema, food allergy, ... Cited by 334 - Related articles - BL Direct - All 7 versions
RM Siegel, FKM Chan, HJ Chun, MJ Lenardo - Nature Immunology, 2000 - nature.com Originally identified as a cell surface receptor that triggered the death of lymphocytes and tumor
cells, it is now recognized that Fas (also known as CD95 or Apo-1) has distinct functions in the
life and death of different cell types in the immune system. Fas signaling may also be ... Cited by 265 - Related articles - All 3 versions
L Salmena, B Lemmers, A Hakem, E Matysiak … - Genes & …, 2003 - genesdev.cshlp.org Defects in death receptor-mediated apoptosis have been linked to cancer and autoimmune disease
in humans. The in vivo role of caspase 8, a component of this pathway, has eluded analysis in
postnatal tissues because of the lack of an appropriate animal model. Targeted disruption ... Cited by 222 - Related articles - BL Direct - All 6 versions
- ►arizona.edu [PDF] SW Fesik - Cell, 2000 - Elsevier Programmed cell death plays a critical role in controlling the number of cells in development
and throughout an organism's life by the removal of cells at the appropriate time. It is an important
biological process for the elimination of unwanted cells such as those with potentially ... Cited by 196 - Related articles - BL Direct - All 10 versions
AM Petros, ET Olejniczak, SW Fesik - BBA-Molecular Cell Research, 2004 - Elsevier The proteins of the Bcl-2 family are important regulators of programmed cell death. Structural
studies of Bcl-2 family members have provided many important insights into their molecular mechanism
of action and how members of this family interact with one another. To date, structural ... Cited by 191 - Related articles - All 3 versions
MR Sprick, E Rieser, H Stahl, A Grosse-Wilde, … - The EMBO …, 2002 - pubmedcentral.nih.gov The involvement of the death adaptor protein FADD and the apoptosis-initiating caspase-8 in
CD95 and TRAIL death signalling has recently been demonstrated by the analysis of the native
death-inducing signalling complex (DISC) that forms upon ligand-induced receptor cross- ... Cited by 185 - Related articles - BL Direct - All 5 versions
- ►nih.gov N Holler, A Tardivel, M Kovacsovics- … - Molecular and Cellular …, 2003 - Am Soc Microbiol The membrane-bound form of Fas ligand (FasL) signals apoptosis in target cells through engagement
of the death receptor Fas, whereas the proteolytically processed, soluble form of FasL does not
induce cell death. However, soluble FasL can be rendered active upon cross-linking. ... Cited by 167 - Related articles - BL Direct - All 8 versions
H Tsutsui, K Matsui, H Okamura, K … - Immunological …, 2000 - interscience.wiley.com Summary: Innate immune response to microbes sometimes determines the nature of the following
specific immune response. Kupffer cells, a potent constituent of innate immunity, play a key role
in developing the type 1 immune response by interleukin (IL)-12 production. Furthermore, ... Cited by 146 - Related articles - BL Direct - All 4 versions
