- ►pharmyaring.com [PDF] SE Inzucchi - Jama, 2002 - Am Med Assoc Context Care of patients with type 2 diabetes has been revolutionized throughout
the past several years—first, by the realization of the importance of tight
glycemic control in forestalling complications, and second, by the ... Cited by 601 - Related articles - BL Direct - All 18 versions
- ►endojournals.org GF Lewis, A Carpentier, K Adeli, A Giacca - Endocrine reviews, 2002 - Endocrine Soc The primary genetic, environmental, and metabolic factors responsible for
causing insulin resistance and pancreatic ß-cell failure and the precise
sequence of events leading to the development of type 2 diabetes are not ... Cited by 514 - Related articles - BL Direct - All 6 versions
RJ Heine, JM Dekker - Diabetologia, 2002 - Springer Type II (non-insulin-dependent) diabetes mellitus is a very prevalent chronic
disease occurring in 2 to 4% of the general population in the Western world and
up to 20 to 30% in high risk populations [1]. Moreover, the global burden ... Cited by 129 - Related articles - BL Direct - All 5 versions
F Pellme, U Smith, T Funahashi, Y Matsuzawa … - Diabetes, 2003 - Am Diabetes Assoc Adiponectin, one of the most abundant gene transcript proteins in human fat
cells, has been shown to improve insulin action and is also suggested to exert
antiatherogenic effects. We measured circulating adiponectin levels and ... Cited by 126 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org YH Yu, HN Ginsberg - Circulation research, 2005 - Am Heart Assoc For many years adipose tissue was viewed as the site where excess energy was
stored, in the form of triglycerides (TGs), and where that energy, when needed
elsewhere in the body, was released in the form of fatty acids (FAs). ... Cited by 104 - Related articles - All 7 versions
U Smith, M Axelsen, E Carvalho, B … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 1999 - interscience.wiley.com ABSTRACT: Adipose tissue only accounts for a relatively small proportion (<10%)
of the peripheral glucose utilization in response to insulin. However, the fat
cells may still play an important role in insulin resistance and Syndrome X ... Cited by 81 - Related articles - BL Direct - All 5 versions
SO Olofsson, P Stillemark-Billton, L Asp - Trends in Cardiovascular Medicine, 2000 - Elsevier Hyperlipidemia is a well-established risk factor for the development of coronary
disease. Increased production of very low-density lipoproteins (VLDL) by the
liver (eg, in type 2 diabetes) is an important reason for hyperlipidemia ... Cited by 64 - Related articles - BL Direct - All 5 versions
W Pratipanawatr, T Pratipanawatr, K Cusi, R … - Diabetes, 2001 - Am Diabetes Assoc Normoglycemic subjects with a strong family history of type 2 diabetes are
insulin resistant, but the mechanism of insulin resistance in skeletal muscle of
such individuals is unknown. The present study was undertaken to determine ... Cited by 62 - Related articles - BL Direct - All 4 versions
Y Yu, L Suo, H Yu, C Wang, H Tang - Diabetes research and clinical practice, 2004 - Elsevier Objective: To evaluate the relationship between insulin resistance and
endothelial function in type 2 diabetes patients with or without
microalbuminuria and to explore the pathophysiological mechanisms of the ... Cited by 52 - Related articles - All 9 versions
- ►fasebj.org PA Jansson, F Pellme, A Hammarstedt, M … - The FASEB Journal, 2003 - FASEB The epidemic increase in type 2 diabetes can be prevented only if markers of
risk can be identified and used for early intervention. We examined the clinical
phenotype of individuals characterized by normal or low IRS-1 protein ... Cited by 55 - Related articles - BL Direct - All 5 versions