RH Hruban, NV Adsay, J Albores-Saavedra, D … - Am J Surg Pathol, 2001 - Springer Most pancreatic cancers are not diagnosed until after the cancer has spread to
other organs and is no longer curable. As a result, the death rate for
pancreatic cancer in this country (34,290/year) is approximately equal to ... Cited by 489 - Related articles - BL Direct - All 9 versions
RH Hruban, M Goggins, J Parsons, SE Kern - Clinical Cancer Research, 2000 - AACR It has been >10 years since Vogelstein and colleagues (1 , 2) proposed a
progression model for colorectal neoplasia in which they hypothesized that the
progression from normal colonic epithelium, to small adenomatous polyps, to ... Cited by 261 - Related articles - BL Direct - All 5 versions
J Koopmann, Z Zhang, N White, J Rosenzweig … - Clinical Cancer Research, 2004 - AACR Experimental Design: In an attempt to improve on current approaches to the
serological diagnosis of pancreatic cancer, we analyzed serum samples from
patients with and without pancreatic cancer using surface-enhanced laser ... Cited by 244 - Related articles - BL Direct - All 8 versions
TP Yeo, RH Hruban, SD Leach, RE Wilentz, TA … - Current problems in cancer, 2002 - Elsevier In the United States the incidence rates of pancreatic cancer increased
threefold between 1920 and 1978, an increase that has also been observed in
other developed countries.[6] Since 1978, incidence rates for men and women ... Cited by 193 - Related articles - BL Direct - All 7 versions
AC Tersmette, GM Petersen, GJA Offerhaus, … - Clinical Cancer Research, 2001 - AACR It has been estimated that familial aggregation and genetic susceptibility play
a role in as many as 10% of patients with pancreatic cancer (PC). The quantified
prospective risk of PC among first-degree relatives of PC patients has not ... Cited by 160 - Related articles - BL Direct - All 5 versions
- ►aacrjournals.org KM Murphy, KA Brune, C Griffin, JE … - Cancer Research, 2002 - AACR It is estimated that familial aggregation and genetic susceptibility play a role
in as many as 10% of pancreatic ductal adenocarcinomas. To investigate the role
of germ-line mutations in the etiology of pancreatic cancer, we have ... Cited by 141 - Related articles - BL Direct - All 5 versions
MI Canto, M Goggins, CJ Yeo, C Griffin, JE … - Clinical Gastroenterology and Hepatology, 2004 - Elsevier Relatives of patients with pancreatic cancer and persons with certain inherited
syndromes are at increased risk for developing pancreatic cancer. We
prospectively evaluated the feasibility of screening for pancreatic ... Cited by 143 - Related articles - BL Direct - All 19 versions
HFA Vasen, NA Gruis, RR Frants, PA van Der … - International Journal of Cancer, 2000 - interscience.wiley.com Familial atypical multiple mole melanoma (FAMMM) is an autosomal dominant
disease characterized by the familial occurrence of malignant melanoma of the
skin and multiple atypical precursor lesions. Germline mutations in the p16 ... Cited by 136 - Related articles - BL Direct - All 4 versions
MI Canto, M Goggins, RH Hruban, GM Petersen, … - Clinical Gastroenterology and Hepatology, 2006 - Elsevier Background & Aims: Individuals with a strong family history of pancreatic cancer
and persons with Peutz-Jeghers syndrome (PJS) have an increased risk for
pancreatic cancer. This study screened for early pancreatic neoplasia and ... Cited by 126 - Related articles - All 32 versions
- ►aacrjournals.org AP Klein, KA Brune, GM Petersen, M Goggins, … - Cancer Research, 2004 - AACR Individuals with a family history of pancreatic cancer have an increased risk of
developing pancreatic cancer. Quantification of this risk provides a rational
basis for cancer risk counseling and for screening for early pancreatic ... Cited by 117 - Related articles - BL Direct - All 6 versions
