- ►yale.edu [PDF] KA Freedberg, E Losina, MC Weinstein, AD … - The New England …, 2001 - nejm.highwire.org Methods We developed a mathematical simulation model of HIV disease, using the CD4 cell
count and HIV RNA level as predictors of the progression of disease. Outcome measures included
life expectancy, life expectancy adjusted for the quality of life, lifetime direct medical costs, ... Cited by 318 - Related articles - BL Direct - All 12 versions
- ►sanbi.ac.za [PDF] GK Robbins, V De Gruttola, RW Shafer, LM … - The New England journal …, 2003 - nejm.org From Harvard Medical School (GKR, MSH) and the Harvard School of Public Health (VDG,
LMS) — both in Boston; the Stanford University Medical Center, Stanford, Calif. (RWS, TCM);
Social & Sci- entific Systems, Silver Spring, Md. (SWS); the Division of AIDS, National ... Cited by 250 - Related articles - BL Direct - All 11 versions
- ►nejm.org GD Sanders, AM Bayoumi, V Sundaram, SP … - The New England …, 2005 - cme.nejm.org Results Given a 1 percent prevalence of unidentified HIV infection, screening increased life expectancy
by 5.48 days, or 4.70 quality-adjusted days, at an estimated cost of $194 per screened
patient, for a cost-effectiveness ratio of $15,078 per quality-adjusted life-year. Screening ... Cited by 231 - Related articles - Cached - All 17 versions
- ►nih.gov RW Shafer - Clinical Microbiology Reviews, 2002 - cmr.highwire.org There are 16 approved human immunodeficiency virus type 1 (HIV-1) drugs belonging to three
mechanistic classes: protease inhibitors, nucleoside and nucleotide reverse transcriptase
(RT) inhibitors, and nonnucleoside RT inhibitors. HIV-1 resistance to these drugs is ... Cited by 202 - Related articles - BL Direct - All 12 versions
- ►annals.org [PDF] MC Weinstein, SJ Goldie, E Losina, CJ … - Annals of internal …, 2001 - Am Coll Physicians Background: Genotypic sequencing for drug-resistant strains of HIV can guide the choice of antiretroviral
therapy. Objective: To assess the cost-effectiveness of genotypic resis- tance testing for patients
acquiring drug resistance through failed treatment (secondary resistance) and those ... Cited by 185 - Related articles - BL Direct - All 8 versions
M Hennessy, D Kelleher, JP Spiers, M … - British Journal of …, 2002 - pubmedcentral.nih.gov St John's Wort (SJW) is widely used in the treatment of depression but concerns have been raised
about its potential to interact with other drugs. Co-administration with SJW has resulted in significant
reductions in trough plasma concentrations of indinavir and cyclosporin [1, 2]. Induction of ... Cited by 151 - Related articles - BL Direct - All 11 versions
- ►nih.gov S De Meyer, H Azijn, D Surleraux, D … - Antimicrobial agents …, 2005 - Am Soc Microbiol The purpose of this study was to characterize the antiviral activity, cytotoxicity, and mechanism
of action of TMC114, a novel human immunodeficiency virus type 1 (HIV-1) protease inhibitor
(PI). TMC114 exhibited potent anti-HIV activity with a 50% effective concentration (EC 50 ) ... Cited by 143 - Related articles - BL Direct - All 13 versions
- ►emory.edu [PDF] RJ Pomerantz, DL Horn - Nature medicine, 2003 - medscape.com In the 20 years since the isolation of HIV-1, modern drug discovery and development have transformed
HIV-1 disease into a treatable, chronic infectious disease ( Table 1 ), although issues of resistance
to current therapy and viral reservoirs remain. The speed of the US Food and Drug ... Cited by 134 - Related articles - BL Direct - All 9 versions
PW Hunt, SG Deeks, B Rodriguez, H Valdez, SB Shade … - Aids, 2003 - journals.lww.com From the a Positive Health Program, San Francisco General Hospital, University of
California, the b Division of General Internal Medicine, Veterans Affairs Medical Center, San
Francisco, California, the c Center for AIDS Research, Case Western Reserve University, ... Cited by 115 - Related articles - BL Direct - All 6 versions
C Piketty, L Weiss, F Thomas, AS Mohamed, L … - The Journal of …, 2001 - UChicago Press Featured in Grist "Another symptom of swine flu: instant amnesia" May 11, 2009 Swine Influenza
Virus: Zoonotic Potential and Vaccination Strategies for the Control of Avian and Swine Influenzas
Eileen Thacker and Bruce Janke Read the veterinary literature on swine flu and you get a ... Cited by 100 - Related articles - BL Direct - All 5 versions
