- ►endojournals.org BL Riggs, S Khosla, LJ Melton III - Endocrine reviews, 2002 - Endocrine Soc Here we review and extend a new unitary model for the pathophysiology of
involutional osteoporosis that identifies estrogen (E) as the key hormone for
maintaining bone mass and E deficiency as the major cause of age-related ... Cited by 535 - Related articles - BL Direct - All 6 versions
AM Matsumoto - Journals of Gerontology Series A: Biological and … - Geron Soc America IT is now well accepted that serum testosterone (T) levels decline progressively
with aging in men (1) (2) (3) (4) (5) . This decline is associated with
alterations in body composition; diminished energy, muscle strength, and ... Cited by 227 - Related articles - BL Direct - All 2 versions
- ►endojournals.org JM Kaufman, A Vermeulen - Endocrine Reviews, 2005 - Endocrine Soc Aging in men is accompanied by a progressive, but individually variable decline
of serum testosterone production, more than 20% of healthy men over 60 yr of age
presenting with serum levels below the range for young men. Albeit the ... Cited by 214 - Related articles - BL Direct - All 5 versions
- ►endojournals.org S Khosla, LJ Melton III, EJ Atkinson, WM O' … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc Estrogen appears to play an important role in determining bone mineral density
in men, but it remains unclear whether estrogen primarily determines peak bone
mass or also affects bone loss in elderly men. Thus, we assessed ... Cited by 195 - Related articles - BL Direct - All 4 versions
- ►endojournals.org L Maffei, Y Murata, V Rochira, G Tubert, C … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc We present the fourth case of an adult man (29 yr old) affected by aromatase
deficiency resulting from a novel homozygous inactivating mutation of the CYP19
(P450 arom ) gene. At first observation, continuing linear growth, ... Cited by 122 - Related articles - All 4 versions
- ►endojournals.org L Gennari, D Merlotti, G Martini, S Gonnelli, … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Male osteoporosis is an increasingly important health problem. It is known that
sex steroid hormones play an important role in regulating bone turnover and bone
mass in males as well as in females. However, the exact mechanism of bone ... Cited by 105 - Related articles - BL Direct - All 5 versions
- ►endojournals.org BZ Leder, KM LeBlanc, DA Schoenfeld, R … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc The physiologic role of androgens and estrogens in the maintenance of normal
bone turnover in men is a fundamental issue in bone biology. To address this
question, we randomized 70 men between the ages of 20 and 44 yr to receive ... Cited by 105 - Related articles - BL Direct - All 4 versions
- ►endojournals.org S Khosla, EJ Atkinson, CR Dunstan, WM O' … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Recent studies have shown that estrogen (E) likely plays a dominant role in
inhibiting bone resorption in normal elderly men. Because both E and T inhibit
osteoclast development and activity, stimulate osteoclast apoptosis, and ... Cited by 100 - Related articles - BL Direct - All 4 versions
WP Olszynski, K Shawn Davison, JD Adachi, … - Clinical therapeutics, 2004 - Elsevier Results: Morbidity after fragility fracture is at least as high in men as in
women, and the rate of fracture-related mortality 1 year hip fracture is
approximately double in men compared with women. The bioavailable fraction ... Cited by 83 - Related articles - All 3 versions
- ►clinchem.org RE Nelson, SK Grebe, DJ O'Kane, RJ Singh - Clinical chemistry, 2004 - Am Assoc Clin Chem Background: Estradiol (E2) and estrone (E1) measurements form an integral part
of the assessment of female reproductive function and have expanding roles in
other fields. However, many E1 and E2 immunoassays have limited functional ... Cited by 76 - Related articles - BL Direct - All 7 versions
