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Scholar Results 1 - 10 of about 396 citing Temple: Placebo-controlled trials and active-control trials in the evaluation of new treatments..... (0.10 sec) 

Scope and impact of financial conflicts of interest in biomedical research: a systematic …

- thecybertramp.com [PDF] 
JE Bekelman, Y Li, CP Gross - Jama, 2003 - Am Med Assoc
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Cited by 694 - Related articles - BL Direct - All 9 versions

Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and …


AM Lincoff, JA Bittl, RA Harrington, F Feit, … - Jama, 2003 - Am Med Assoc
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to make your experience on this site better. ... Add to CiteULike Add to ...
Cited by 515 - Related articles - BL Direct - All 8 versions

Placebo response in studies of major depression: variable, substantial, and growing


BT Walsh, SN Seidman, R Sysko, M Gould - Jama, 2002 - Am Med Assoc
Context Intense debate persists about the need for placebo-controlled groups in
clinical trials of medications for major depressive disorder (MDD). There is
continuing interest in the development of new medications, but because ...
Cited by 401 - Related articles - BL Direct - All 4 versions

Selective publication of antidepressant trials and its influence on apparent efficacy

- woodymatters.com [PDF] 
EH Turner, AM Matthews, E Linardatos, RA … - New England Journal of Medicine, 2008 - content.nejm.org
Results Among 74 FDA-registered studies, 31%, accounting for 3449 study
participants, were not published. Whether and how the studies were published
were associated with the study outcome. A total of 37 studies viewed by the ...
Cited by 315 - Related articles - BL Direct - All 25 versions

Herbal remedies


PAGM De Smet - New England Journal of Medicine, 2002 - content.nejm.org
Several countries (eg, Germany, France, Sweden, and Australia) have implemented
strategies for licensing herbal remedies. In Germany, such products can be
registered as medicines on the basis of information in approximately 300 ...
Cited by 301 - Related articles - All 6 versions

[PDF] The pharmacological treatment of urinary incontinence


KE Andersson, R Appell, LD Cardozo, C … - BJU international, 1999 - icsoffice.org
Page 1. Committee 10 Pharmacological Treatment of Urinary Incontinence Chairman
KE ANDERSSON (SWEDEN) Members R. APPELL (USA), L. CARDOZO (UK), C. CHAPPLE (UK), ...
Cited by 238 - Related articles - BL Direct - All 9 versions

Lessons from the glitazones: a story of drug development


EAM Gale - The Lancet, 2001 - Elsevier
Troglitazone, the first in the thiazolidinedione class of oral hypoglycaemic
agents, was launched in the USA in March, 1997. It reached Europe later that
year, only to be withdrawn within weeks on the grounds of liver toxicity. ...
Cited by 176 - Related articles - BL Direct - All 5 versions

The ethics of placebo-controlled trials--a middle ground


EJ Emanuel, FG Miller - The New England journal of medicine, 2001 - nejm.highwire.org
The first placebo-controlled trial was probably conducted in 1931, when
sanocrysin was compared with distilled water for the treatment of tuberculosis.
1 Ever since then, placebo-controlled trials have been controversial, ...
Cited by 164 - Related articles - BL Direct - All 16 versions

Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 2: …

- annals.org
SS Ellenberg, R Temple - Annals of Internal Medicine, 2000 - Am Coll Physicians
Placebo controls are commonly used in clinical trials of investigational
treatments because they have important advantages. In recent years, some have
criticized the use of placebo-controlled trials when effective alternative ...
Cited by 166 - Related articles - BL Direct - All 7 versions

A critique of clinical equipoise: Therapeutic misconception in the ethics of clinical trials

- uwo.ca [PDF] 
FG Miller, H Brody - Hastings Center Report, 2003 - jstor.org
T he prevailing ethical perspective on clinical trials holds that physi-
cian-investigators can discharge their "therapeutic obligation" to patients in
the context of randomized clinical tri- als (RCTs) as long as treatments ...
Cited by 136 - Related articles - BL Direct - All 6 versions


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