- ►annals.org R Temple, SS Ellenberg - Annals of Internal Medicine, 2000 - Am Coll Physicians In recent years, several authors have argued that placebo-controlled trials are
invariably unethical when known effective therapy is available for the condition
being studied, regardless of the condition or the consequences of deferring ... Cited by 395 - Related articles - BL Direct - All 9 versions
- ►zhaoys.com [PDF] HR Black, WJ Elliott, G Granditis, P Grambsch - ACC Current Journal Review, 2003 - Elsevier Methods: A double-blind randomized trial in 16,602 subjects with hypertension
and 1 or more other CV risk factors. The primary end point was a myocardial
infarction, stroke or CV death. The study was designed to last 5 years. ... Cited by 342 - Related articles - BL Direct - All 14 versions
KE Andersson, R Appell, LD Cardozo, C … - BJU international, 1999 - icsoffice.org Page 1. Committee 10 Pharmacological Treatment of Urinary Incontinence Chairman
KE ANDERSSON (SWEDEN) Members R. APPELL (USA), L. CARDOZO (UK), C. CHAPPLE (UK), ... Cited by 236 - Related articles - BL Direct - All 9 versions
EAM Gale - The Lancet, 2001 - Elsevier Troglitazone, the first in the thiazolidinedione class of oral hypoglycaemic
agents, was launched in the USA in March, 1997. It reached Europe later that
year, only to be withdrawn within weeks on the grounds of liver toxicity. ... Cited by 174 - Related articles - BL Direct - All 5 versions
EJ Emanuel, FG Miller - The New England journal of medicine, 2001 - nejm.highwire.org The first placebo-controlled trial was probably conducted in 1931, when
sanocrysin was compared with distilled water for the treatment of tuberculosis.
1 Ever since then, placebo-controlled trials have been controversial, ... Cited by 164 - Related articles - BL Direct - All 16 versions
RB D'Agostino, JM Massaro, LM Sullivan - Statistics in Medicine, 2002 - haberle.com STATISTICS IN MEDICINE Statist. Med. 2003; 22:169–186 (DOI: 10.1002/sim.1425) ... Non-inferiority trials: design concepts and issues – the encounters of
academic consultants in statistics ... Ralph B. D'Agostino Sr.1;2;∗;† ... Cited by 128 - Related articles - View as HTML - BL Direct - All 8 versions
FG Gilliam, F Veloso, MAM Bomhof, SK Gazda, … - Neurology, 2003 - AAN Enterprises Methods: Adults and children ( 3 years of age) were eligible if the maximum
interval since epilepsy diagnosis was 3 years and patients had one to six
partial-onset seizures during a 3-month retrospective baseline. At study ... Cited by 109 - Related articles - BL Direct - All 4 versions
- ►annals.org [PDF] S Kaul, GA Diamond - Annals of internal medicine, 2006 - Am Coll Physicians Active-control noninferiority trials are being performed with increas- ing
frequency when standard placebo-controlled trials are consid- ered unethical.
Three attributes are optimally required to establish noninferiority: 1) The ... Cited by 93 - Related articles - BL Direct - All 6 versions
JL Halperin - American Heart Journal, 2003 - Elsevier SPORTIF III is a randomized, open-label, parallel-group study with blinded event
assessment involving 3407 patients at 259 sites in 23 countries. SPORTIF V is
similar, but with double-blind treatment allocation involving 3922 patients ... Cited by 91 - Related articles - All 3 versions
M Rothmann, N Li, G Chen, GYH Chi, R … - Statistics in Medicine, 2002 - sctweb.org STATISTICS IN MEDICINE Statist. Med. 2003; 22:239–264 (DOI: 10.1002/sim.1400) ... Design and analysis of non-inferiority mortality trials in oncology ‡;¶ ... Mark Rothmann1;∗;† , Ning Li1, Gang Chen1, George YH Chi1, Robert ... Cited by 85 - Related articles - View as HTML - BL Direct - All 6 versions
