- ►shouxi.net VJ Navarro, JR Senior - The New England journal of medicine, 2006 - nejm.highwire.org In this review, we define hepatotoxicity as injury to the liver that is associated with impaired liver
function caused by exposure to a drug or another noninfectious agent. The distinction between
injury and function is important, because it is mainly when function is impaired that ... Cited by 196 - Related articles - BL Direct - All 16 versions
P Glasziou, J Vandenbroucke, I Chalmers - British Medical Journal, 2004 - bmj.com The widespread use of hierarchies of evidence that grade research studies according to their
quality has helped to raise awareness that some forms of evidence are more trustworthy than
others. This is clearly desirable. However, the simplifications involved in creating and ... Cited by 155 - Related articles - BL Direct - All 9 versions
JP Vandenbroucke, E von Elm, DG Altman, PC … - …, 2007 - medicine.plosjournals.org Much medical research is observational. The reporting of observational studies is often of insufficient
quality. Poor reporting hampers the assessment of the strengths and weaknesses of a study
and the generalisability of its results. Taking into account empirical evidence and ... Cited by 128 - Related articles - Cached - BL Direct - All 34 versions
WR Hersh - 2008 - books.google.com William Hersh, MD Professor and Chair Department of Medical Informatics & Clinical Epidemiology
Oregon Health & Science University 3181 SW Sam Jackson Park Rd. BICC Portland, OR, USA
97239 Series Editors Marion J. Ball, Ed.D Kathryn J. Hannah Fellow, Center for ... Cited by 102 - Related articles - All 5 versions
- ►nih.gov [PDF] JK Aronson, M Hauben - British Medical Journal, 2006 - bmj.com Many adverse drug reactions are first reported anecdotally. Anecdotal reports, by which we mean
either individual cases or small case series, are generally regarded as providing poor quality
evidence. They therefore usually require formal verification through robust ... Cited by 60 - Related articles - BL Direct - All 9 versions
- ►highwire.org BHC Stricker, BM Psaty - BMJ, 2004 - bmjcom.highwire.org Although some will question the use of the term experiment on formal grounds, most experts
will likely agree that the widespread marketing of a new drug is in fact a large experiment on
a population. This is especially the case when it concerns a novel molecular entity with ... Cited by 57 - Related articles - BL Direct - All 10 versions
- ►nih.gov YK Loke, D Price, S Derry, JK Aronson - British Medical Journal, 2006 - bmj.com Data sources We evaluated all case reports of adverse drug reactions published in 1997 in five
medical journals. Reports were excluded if the adverse reaction had previously been described
in earlier publications and was already listed in the product information of the drug ... Cited by 42 - Related articles - BL Direct - All 8 versions
C Lestuzzi, E Viel, E Picano, N Meneguzzo - The American journal of medicine, 2001 - Elsevier A 53-year-old woman, a former smoker with a positive family history of coronary artery
disease, had metastatic (hepatic and peritoneal) colorectal adenocarcinoma diagnosed in May
1999. She had no manifest cardiac disease. She received 21 courses of chemotherapy (5- ... Cited by 33 - Related articles - BL Direct - All 6 versions
- ►psu.edu [PDF] JS Sekhon - Perspectives on Politics, 2004 - Cambridge Univ Press In contrast to statistical methods, a number of case study methods—collectively referred to as
Mill's methods, used by generations of social science researchers—only consider deterministic
relationships. They do so to their detriment because heeding the basic lessons of ... Cited by 31 - Related articles - BL Direct - All 9 versions
