- ►212.227.202.189 [PDF] SJ Winawer - Best Practice & Research Clinical Gastroenterology, 2007 - Elsevier Colorectal cancer is a worldwide problem having global increases in the number
of cases and deaths because of the expanding and aging of the population in both
developing and developed countries. Screening methods are available which ... Cited by 2725 - Related articles - BL Direct - All 63 versions
JJP Gille, FBL Hogervorst, G Pals, JTH … - British journal of cancer, 2002 - pubmedcentral.nih.gov Hereditary non-polyposis colorectal cancer is an autosomal dominant condition
due to germline mutations in DNA-mismatch-repair genes, in particular MLH1, MSH2
and MSH6. Here we describe the application of a novel technique for the ... Cited by 132 - Related articles - BL Direct - All 9 versions
- ►bmj.com LA Houghton, EL Calvert, NA Jackson, P … - British Medical Journal, 2002 - gut.bmj.com ABSTRACT Background and objectives: We have previously shown that hypnosis can
be used to study the effect of different emotions on the motility of the
gastrointestinal tract. These studies demonstrated that both anger and ... Cited by 51 - Related articles - BL Direct - All 8 versions
- ►bmj.com A Brieger, J Trojan, J Raedle, G Plotz, S … - British Medical Journal, 2002 - gut.bmj.com Background: Germline mutations in the mismatch repair (MMR) genes hMLH1 and
hMSH2 can cause hereditary non-polyposis colorectal cancer (HNPCC). However, the
functional in vitro analysis of hMLH1 and hMSH2 mutations remains difficult. Cited by 40 - Related articles - BL Direct - All 9 versions
CL Wright, ID Stewart - The American journal of surgical pathology, 2003 - journals.lww.com Defects in the mismatch repair (MMR) genes hMLH1 and hMSH2 have been found in
10% to 20% of sporadic colorectal carcinomas and also many cases of hereditary
nonpolyposis colorectal cancer syndrome. Patients with these tumors have an ... Cited by 34 - Related articles - BL Direct - All 5 versions
W Kievit, J de Bruin, EMM Adang, MJL … - Clinical genetics, 2004 - interscience.wiley.com Present guidelines to identify hereditary non-polyposis colorectal cancer
(HNPCC) families are criticized for limitations in accuracy. The Amsterdam
criteria I and II (AC I and AC II) are used to predict a germline mutation ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►nih.gov G Plotz, J Raedle, A Brieger, J Trojan, S … - Nucleic acids research, 2003 - Oxford Univ Press Mismatch repair is a highly conserved system that ensures replication fidelity
by repairing mispairs after DNA synthesis. In humans, the two protein
heterodimers hMutS (hMSH2-hMSH6) and hMutL (hMLH1-hPMS2) constitute the ... Cited by 26 - Related articles - BL Direct - All 7 versions
M Bettstetter, S Dechant, P Ruemmele, M … - Clinical Cancer Research, 2007 - AACR Purpose: Promoter hypermethylation occurs frequently in tumors and leads to
silencing of tumor-relevant genes like tumor suppressor genes. In a subset of
sporadic colorectal cancers (CRC), inactivation of the mismatch repair gene ... Cited by 25 - Related articles - BL Direct - All 4 versions
SB Gruber - Gastroenterology, 2006 - Elsevier Genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC), or what
is now more appropriately known as Lynch syndrome, has become the standard of
care for patients with features suggestive of this syndrome and their ... Cited by 24 - Related articles - All 9 versions
N Lubomierski, G Plotz, M Wormek, K Engels, … - CA A Cancer Journal for Clinicians - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 22 - Related articles - BL Direct - All 3 versions