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Scholar Results 1 - 10 of about 59 citing Raedle: Bethesda guidelines: relation to microsatellite instability and MLH1 promoter methylation.... (0.07 sec) 

Colorectal cancer screening

- 212.227.202.189 [PDF] 
SJ Winawer - Best Practice & Research Clinical Gastroenterology, 2007 - Elsevier
Colorectal cancer is a worldwide problem having global increases in the number
of cases and deaths because of the expanding and aging of the population in both
developing and developed countries. Screening methods are available which ...
Cited by 2725 - Related articles - BL Direct - All 63 versions

Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel …


JJP Gille, FBL Hogervorst, G Pals, JTH … - British journal of cancer, 2002 - pubmedcentral.nih.gov
Hereditary non-polyposis colorectal cancer is an autosomal dominant condition
due to germline mutations in DNA-mismatch-repair genes, in particular MLH1, MSH2
and MSH6. Here we describe the application of a novel technique for the ...
Cited by 132 - Related articles - BL Direct - All 9 versions

Visceral sensation and emotion: a study using hypnosis

- bmj.com
LA Houghton, EL Calvert, NA Jackson, P … - British Medical Journal, 2002 - gut.bmj.com
ABSTRACT Background and objectives: We have previously shown that hypnosis can
be used to study the effect of different emotions on the motility of the
gastrointestinal tract. These studies demonstrated that both anger and ...
Cited by 51 - Related articles - BL Direct - All 8 versions

Transient mismatch repair gene transfection for functional analysis of genetic hMLH1 and …

- bmj.com
A Brieger, J Trojan, J Raedle, G Plotz, S … - British Medical Journal, 2002 - gut.bmj.com
Background: Germline mutations in the mismatch repair (MMR) genes hMLH1 and
hMSH2 can cause hereditary non-polyposis colorectal cancer (HNPCC). However, the
functional in vitro analysis of hMLH1 and hMSH2 mutations remains difficult.
Cited by 40 - Related articles - BL Direct - All 9 versions

Histopathology and mismatch repair status of 458 consecutive colorectal carcinomas


CL Wright, ID Stewart - The American journal of surgical pathology, 2003 - journals.lww.com
Defects in the mismatch repair (MMR) genes hMLH1 and hMSH2 have been found in
10% to 20% of sporadic colorectal carcinomas and also many cases of hereditary
nonpolyposis colorectal cancer syndrome. Patients with these tumors have an ...
Cited by 34 - Related articles - BL Direct - All 5 versions

Current clinical selection strategies for identification of hereditary non-polyposis colorectal …


W Kievit, J de Bruin, EMM Adang, MJL … - Clinical genetics, 2004 - interscience.wiley.com
Present guidelines to identify hereditary non-polyposis colorectal cancer
(HNPCC) families are criticized for limitations in accuracy. The Amsterdam
criteria I and II (AC I and AC II) are used to predict a germline mutation ...
Cited by 33 - Related articles - BL Direct - All 5 versions

N-terminus of hMLH1 confers interaction of hMutL {alpha} and hMutL {beta} with hMutS { …

- nih.gov
G Plotz, J Raedle, A Brieger, J Trojan, S … - Nucleic acids research, 2003 - Oxford Univ Press
Mismatch repair is a highly conserved system that ensures replication fidelity
by repairing mispairs after DNA synthesis. In humans, the two protein
heterodimers hMutS (hMSH2-hMSH6) and hMutL (hMLH1-hPMS2) constitute the ...
Cited by 26 - Related articles - BL Direct - All 7 versions

Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite- …


M Bettstetter, S Dechant, P Ruemmele, M … - Clinical Cancer Research, 2007 - AACR
Purpose: Promoter hypermethylation occurs frequently in tumors and leads to
silencing of tumor-relevant genes like tumor suppressor genes. In a subset of
sporadic colorectal cancers (CRC), inactivation of the mismatch repair gene ...
Cited by 25 - Related articles - BL Direct - All 4 versions

New developments in Lynch syndrome (hereditary nonpolyposis colorectal cancer) and …


SB Gruber - Gastroenterology, 2006 - Elsevier
Genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC), or what
is now more appropriately known as Lynch syndrome, has become the standard of
care for patients with features suggestive of this syndrome and their ...
Cited by 24 - Related articles - All 9 versions

BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable …


N Lubomierski, G Plotz, M Wormek, K Engels, … - CA A Cancer Journal for Clinicians - interscience.wiley.com
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Cited by 22 - Related articles - BL Direct - All 3 versions


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