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Scholar Results 1 - 10 of about 84 citing Smith: Rheumatoid arthritis--a molecular understanding. (0.30 sec) 

Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: results of …


SB Cohen, P Emery, MW Greenwald, M … - Arthritis Care & Research - interscience.wiley.com
Dr. Cohen has received honoraria (less than $10,000 each) from Genentech, Biogen
Idec, Scios, and Amgen. Dr. Emery has received honoraria (less than $10,000)
from Genentech. Dr. Furie has received honoraria (less than $10,000 each) ...
Cited by 287 - Related articles - BL Direct - All 5 versions

Synovial fibroblasts: key players in rheumatoid arthritis

- oxfordjournals.org
LC Huber, O Distler, I Tarner, RE Gay, S Gay, … - Rheumatology, 2006 - Br Soc Rheumatology
Rheumatoid arthritis (RA) is a chronic autoimmune-disease of unknown origin that
primarily affects the joints and ultimately leads to their destruction. The
involvement of immune cells is a general hallmark of autoimmune-related ...
Cited by 79 - Related articles - BL Direct - All 5 versions

Adalimumab (Humira®) restores clinical response in patients with secondary loss of efficacy …


MC Wick, S Ernestam, S Lindblad, J Bratt, L … - Scandinavian journal of rheumatology, 2005 - informahealthcare.com
Results: In group A, the baseline disease activity score 28 (DAS28) at
infliximab institution was 5.5±0.2. During infliximab treatment, the mean best
DAS28 was 3.7±0.2 (p<0.001), but increased to 5.2±0.3 when infliximab was ...
Cited by 69 - Related articles - BL Direct - All 6 versions

CC and CXC chemokine receptors mediate migration, proliferation, and matrix …


R García-Vicuña, MV Gómez-Gaviro, MJ … - Arthritis Care & Research - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 58 - Related articles - All 4 versions

Rheumatoid arthritis: an overview of new and emerging therapies


T Doan, E Massarotti - The Journal of Clinical Pharmacology, 2005 - jclinpharm.highwire.org
Rheumatoid arthritis (RA) is a chronic, inflammatory, systemic autoimmune
disorder characterized by symmetric inflammation of synovial joints leading to
progressive erosion of cartilage and bone. The aim of treatment is to ...
Cited by 48 - Related articles - BL Direct - All 5 versions

Matrix metalloproteinases-3,-8,-9 as markers of disease activity and joint damage progression …

- bmj.com
I Tchetverikov, LR Lard, J DeGroot, N … - British Medical Journal, 2003 - ard.bmj.com
Results: During the two years joint damage progressed from 0 to 10 (median Sharp
score, p<0.001). Stable levels of pro-MMP-3 and a significant decrease in the
levels of pro-MMP-8 and -9 and 2 M/MMP complexes were seen throughout the ...
Cited by 44 - Related articles - BL Direct - All 10 versions

CD40-mediated immune-nonimmune cell interactions induce mucosal fibroblast chemokines …

- 192.35.79.232 [PDF] 
JD Vogel, GA West, S Danese, C de la Motte, MH … - Gastroenterology, 2004 - Elsevier
: The CD40 pathway is a key mediator of inflammation and autoimmunity. We
investigated cell adhesion molecule (CAM) up-regulation and chemokine production
by CD40-positive human intestinal fibroblasts (HIF) and microvascular ...
Cited by 41 - Related articles - BL Direct - All 20 versions

Contribution of reactive oxygen species to cartilage degradation in rheumatic diseases: …


J Schiller, B Fuchs, J Arnhold, K Arnold - Current medicinal chemistry, 2003 - ingentaconnect.com
Institute of Medical Physics and Biophysics, Medical Department, University of
Leipzig, Liebigstr. 27, D-04103 Leipzig, Germany Abstract: Inflammatory joint
diseases are of considerable socio-economic significance. However, ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-{alpha}- …

- oxfordjournals.org
JM Hansen, H Zhang, DP Jones - Toxicological Sciences, 2006 - Soc Toxicology
Tumor necrosis factor- (TNF- ) is a cytokine that is involved in numerous
pathologies, in part through stimulation of the mitochondrial production of
reactive oxygen species (ROS). Previous studies show that in addition to ...
Cited by 38 - Related articles - All 5 versions

Signal transduction pathways and transcription factors as therapeutic targets in …


SW Tas, PHJ Remans, KA Reedquist, PP Tak - Current pharmaceutical design, 2005 - ingentaconnect.com
Abstract; Many chronic inflammatory diseases are associated with deregulated
intracellular signal transduction pathways. Resultant pathogenic interactions
between immune and stromal cells lead to changes in cell activation, ...
Cited by 32 - Related articles - All 5 versions


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