- ►bmj.com M Luisetti, N Seersholm - Thorax, 2004 - pubmedcentral.nih.gov In the last 40 years, following the publication of the seminal paper by Laurell
and Eriksson,1 there have been significant advances in the understanding of
genetic abnormalities related to a1-antitrypsin (AAT) deficiency and of the ... Cited by 81 - Related articles - BL Direct - All 11 versions
- ►chestpubs.org NA Molfino - Chest, 2004 - chestjournal.chestpubs.org COPD is a complex mix of signs and symptoms in patients with chronic bronchitis
and emphysema, diseases that largely result from cigarette smoking. Not all
smokers, however, acquire COPD, and COPD can develop in nonsmokers. In the ... Cited by 72 - Related articles - BL Direct - All 7 versions
- ►rupress.org M Dahl, A Tybjaerg-Hansen, P Schnohr, BG … - Journal of Experimental Medicine, 2004 - jem.rupress.org Reduced levels of wild-type mannose-binding lectin (MBL) may increase
susceptibility for infection, other common diseases, and death. We investigated
associations between MBL deficiency and risk of infection, other common ... Cited by 70 - Related articles - BL Direct - All 5 versions
- ►bmj.com CP Hersh, M Dahl, NP Ly, CS Berkey, BG … - British Medical Journal, 2004 - thorax.bmj.com Results: In 16 studies that reported COPD as a categorical outcome, the combined
odds ratio (OR) for PI MZ versus PI MM (normal genotype) was 2.31 (95% CI 1.60
to 3.35). The summary OR was higher in case-control studies (OR 2.97; 95% ... Cited by 59 - Related articles - BL Direct - All 10 versions
- ►atsjournals.org AG Schwartz, JC Ruckdeschel - American journal of respiratory and critical care …, 2006 - Am Thoracic Soc Lung cancer continues to be the leading cause of cancer death, and although most
lung cancer is attributable to cigarette smoking, underlying genetic
susceptibility is suggested by studies demonstrating familial aggregation. ... Cited by 38 - Related articles - BL Direct - All 6 versions
FJ De Serres, I Blanco, E Fernandez-Bustillo - Clinical genetics, 2003 - alfa1.org.es Alpha-1-antitrypsin deficiency (AAT deficiency) is one of the most common
serious hereditary disorders in the world because it affects all major racial
subgroups worldwide and there are at least 120.5 million carriers and ... Cited by 31 - Related articles - View as HTML - BL Direct - All 10 versions
FJ De Serres, I Blanco, E Fernandez-Bustillo - Clinical genetics, 2003 - interscience.wiley.com Alpha-1-antitrypsin deficiency (AAT deficiency) is one of the most common
serious hereditary disorders in the world, as its affects all major racial
subgroups worldwide, and there are an estimated 120.5 million carriers and ... Cited by 30 - Related articles - BL Direct - All 6 versions
- ►ersj.org.uk M Dahl, CP Hersh, NP Ly, CS Berkey, EK … - European Respiratory Journal, 2005 - ersj.org.uk Aggregating data from six studies, the odds ratio (OR) for COPD in PI SZ
compound heterozygotes compared with PI MM (normal) individuals was
significantly increased at 3.26 (95% confidence intervals (CI): ... Cited by 26 - Related articles - All 7 versions
Z Urban, J Gao, FM Pope, EC Davis - Journal of Investigative Dermatology, 2005 - nature.com Cutis laxa (CL) is a heterogeneous group of genetic and acquired disorders with
at least two autosomal dominant forms caused by mutations in the elastin and
fibulin-5 genes, respectively. To define the molecular basis of CL in ... Cited by 25 - Related articles - BL Direct - All 8 versions
