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Scholar Results 1 - 10 of about 86 citing May: Mixed hepatocellular-cholestatic liver injury after pioglitazone therapy. (0.13 sec) 

Drug-induced hepatotoxicity

- uab.edu [PDF] 
WM Lee - The New England journal of medicine, 2003 - nejm.highwire.org
In the past five years, two drugs have been withdrawn from the market by the
Food and Drug Administration (FDA) for causing severe liver injury, a potential
danger that had not been fully recognized in the course of the preapproval ...
Cited by 665 - Related articles - BL Direct - All 22 versions

Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence

- adisonline.com [PDF] 
M Diamant, RJ Heine - Drugs, 2003 - ingentaconnect.com
Abstract. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . 1373 1. Thiazolidinediones: Basic Aspects and Mode of Action ...
Cited by 174 - Related articles - BL Direct - All 9 versions

Interim results of a pilot study demonstrating the early effects of the PPAR-[gamma] ligand …


BA Neuschwander-Tetri, EM Brunt, KR … - Journal of hepatology, 2003 - Elsevier
Background/Aims: Hyperinsulinemia may cause hepatic steatosis and non-alcoholic
steatohepatitis (NASH). The aims of this pilot study were to examine the safety
of using the insulin-sensitizing peroxisomal proliferator activated ...
Cited by 95 - Related articles - All 11 versions

Pioglitazone and metformin in obese women with polycystic ovary syndrome not optimally …

- oxfordjournals.org
CJ Glueck, A Moreira, N Goldenberg, L Sieve … - Human Reproduction, 2003 - ESHRE
BACKGROUND: In an observational study of 13 women with polycystic ovary syndrome
(PCOS) not optimally responsive to metformin diet, we assessed the efficacy and
safety of addition of pioglitazone. We also compared these 13 women to 26 ...
Cited by 75 - Related articles - BL Direct - All 8 versions

Glycemic control with glyburide/metformin tablets in combination with rosiglitazone in …


GE Dailey, MA Noor, JS Park, S Bruce, FT … - The American journal of medicine, 2004 - Elsevier
Following an open-label, lead-in phase to optimize the dosing of
glyburide/metformin tablets, 365 patients randomly received additive therapy
comprising rosiglitazone (4 mg once daily) or placebo for 24 weeks. Based ...
Cited by 64 - Related articles - All 9 versions

Pioglitazone: a review of its use in type 2 diabetes mellitus

- adisonline.com [PDF] 
J Waugh, GM Keating, GL Plosker, S … - Drugs, 2006 - ingentaconnect.com
0012-6667/06/0001-0085/$44.95/0  2006 Adis Data Information BV. All rights
reserved. ... A Review of its Use in Type 2 Diabetes Mellitus ... John Waugh,
Gillian M. Keating, Greg L. Plosker, Stephanie Easthope and Dean M. Robinson
Cited by 64 - Related articles - BL Direct - All 7 versions

Hepatotoxicity of thiazolidinediones


WL Isley - eds, 2003 - informahealthcare.com
Thiazolidinediones are insulin sensitisers now widely used for the treatment of
Type 2 diabetes mellitus. The initial marketed drug in this class, troglitazone,
was removed from the market worldwide after approximately 3 years of use ...
Cited by 53 - Related articles - BL Direct - All 9 versions

Hepatotoxicity of the thiazolidinediones


KG Tolman, J Chandramouli - Clinics in Liver Disease, 2003 - Elsevier
Type II diabetes mellitus is a chronic metabolic disorder characterized by
hyperglycemia secondary to inadequate insulin secretion. The earliest detectable
abnormality is peripheral insulin resistance, leading to impaired uptake of ...
Cited by 52 - Related articles - BL Direct - All 2 versions

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

- aspetjournals.org
J Sahi, CB Black, GA Hamilton, X Zheng, S … - Drug Metabolism and Disposition, 2003 - ASPET
Rosiglitazone and pioglitazone are thiazolidinediones used for treatment of
noninsulin-dependent diabetes mellitus. These compounds, along with
troglitazone, were evaluated for the ability to induce cytochrome P450 ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Narrative review: hepatobiliary disease in type 2 diabetes mellitus

- annals.org [PDF] 
KG Tolman, V Fonseca, MH Tan, A Dalpiaz - Annals of internal medicine, 2004 - Am Coll Physicians
Diabetes mellitus is the fifth leading cause of death in the United States; 17
million people are affected. Liver disease is one of the leading causes of death
in persons with type 2 diabetes. The standardized mortality rate for death ...
Cited by 51 - Related articles - All 5 versions


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