- ►shouxi.net N Galie, HA Ghofrani, A Torbicki, RJ Barst, … - The New England journal of medicine, 2005 - nejm.highwire.org Methods In this double-blind, placebo-controlled study, we randomly assigned 278
patients with symptomatic pulmonary arterial hypertension (either idiopathic or
associated with connective-tissue disease or with repaired congenital ... Cited by 557 - Related articles - BL Direct - All 9 versions
HA Ghofrani, R Wiedemann, F Rose, RT … - The Lancet, 2002 - Elsevier Pulmonary vascular resistance index was reduced by nitric oxide (−21·9%, 95%
Cl −14·1 to −36·2), epoprostenol (−36·9%, −24·4 to −59·6), and
sildenafil (−32·5%, −10·2 to −54·1). However, ratio of pulmonary ... Cited by 436 - Related articles - All 7 versions
- ►westhertshospitals.nhs.uk [PDF] JR Runo, JE Loyd - The Lancet, 2003 - Elsevier Primary pulmonary hypertension (PPH) is a rare disorder characterised by raised
pulmonary-artery pressure in the absence of secondary causes. Precapillary
pulmonary arteries are affected by medial hypertrophy, intimal fibrosis, ... Cited by 300 - Related articles - All 13 versions
- ►onlinejacc.org HA Ghofrani, F Rose, RT Schermuly, H … - Journal of the American College of Cardiology, 2003 - Elsevier We sought to investigate the impact of adjunct sildenafil on exercise capacity
and hemodynamic parameters in patients with pulmonary arterial hypertension
(PAH) who fulfilled predefined criteria of deterioration despite ongoing ... Cited by 264 - Related articles - BL Direct - All 15 versions
- ►atsjournals.org HA Ghofrani, RT Schermuly, F Rose, R … - American journal of respiratory and critical care …, 2003 - Am Thoracic Soc Only a small percentage of patients with chronic thromboembolic pulmonary
hypertension are eligible for pulmonary thrombendarterectomy. We investigated
the effects of oral sildenafil on hemodynamics and exercise capacity in 12 ... Cited by 215 - Related articles - BL Direct - All 6 versions
- ►nih.gov RT Schermuly, E Dony, HA Ghofrani, S … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Progression of pulmonary hypertension is associated with increased proliferation
and migration of pulmonary vascular smooth muscle cells. PDGF is a potent
mitogen and involved in this process. We now report that the PDGF receptor ... Cited by 208 - Related articles - BL Direct - All 11 versions
- ►ersjournals.com MM Hoeper, C Faulenbach, H Golpon, J … - European Respiratory Journal, 2004 - Eur Respiratory Soc The 6MWD at baseline was 346±66 m and improved to 403±80 m 3 months after
introduction of bosentan treatment. However, this effect was not sustained and,
after an interval of 11±5 months, the walk distance had declined to ... Cited by 167 - Related articles - BL Direct - All 8 versions
- ►onlinejacc.org HA Ghofrani, R Voswinckel, F Reichenberger … - Journal of the American College of Cardiology, 2004 - Elsevier Sixty consecutive PAH patients (New York Heart Association functional class II
to IV) who underwent right heart catheterization received short-term nitric
oxide (NO) inhalation and were subsequently assigned to oral intake of 50 ... Cited by 158 - Related articles - BL Direct - All 19 versions
HA Ghofrani, W Seeger, F Grimminger - New England Journal of Medicine, 2005 - content.nejm.org Page 1. The new england journal of medicine n engl j med 353;13
www.nejm.org september 29, 2005 1412 correspondence Imatinib for ... Cited by 145 - Related articles - All 6 versions
- ►annals.org [PDF] HA Ghofrani, F Reichenberger, MG Kohstall, … - Annals of internal medicine, 2004 - Am Coll Physicians Background: Alveolar hypoxia causes pulmonary hypertension and enhanced right
ventricular afterload, which may impair exer- cise tolerance. The
phosphodiesterase-5 inhibitor sildenafil has been reported to cause ... Cited by 122 - Related articles - BL Direct - All 10 versions
