- Free from Publisher RA DeFronzo, RE Ratner, J Han, DD Kim, MS … - Diabetes care, 2005 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A triple-blind, placebo-controlled, 30-week study
at 82 US sites was performed with 336 randomized patients. In all, 272 patients
completed the study. The intent-to-treat population baseline was 53 ± 10 ... Cited by 637 - Related articles - All 6 versions
- Free from Publisher DM Kendall, MC Riddle, J Rosenstock, D … - Diabetes Care, 2005 - Am Diabetes Assoc RESULTS—Week 30 A1C changes from baseline (±SE) were −0.8 ± 0.1% (10 μg),
−0.6 ± 0.1% (5 μg), and +0.2 ± 0.1% (placebo; adjusted P < 0.0001 vs.
placebo), yielding placebo-adjusted reductions of −1.0% (10 μg) and ... Cited by 543 - Related articles - All 11 versions
- ►diabetesjournals.org JB Buse, RR Henry, J Han, DD Kim, MS … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—At week 30, HbA 1c changes from baseline were −0.86 ± 0.11, −0.46
± 0.12, and 0.12 ± 0.09% (±SE) in the 10-μg, 5-μg, and placebo arms,
respectively (adjusted P < 0.001). Of evaluable subjects with baseline HbA ... Cited by 454 - Related articles - BL Direct - All 13 versions
- ►cell.com J Lin, PH Wu, PT Tarr, KS Lindenberg, J St- … - Cell, 2004 - Elsevier PGC-1α is a coactivator of nuclear receptors and other transcription factors
that regulates several metabolic processes, including mitochondrial biogenesis
and respiration, hepatic gluconeogenesis, and muscle fiber-type switching. ... Cited by 278 - Related articles - All 26 versions
A Uygun, A Kadayifci, AT Isik, T Ozgurtas, S … - Alimentary Pharmacology and Therapeutics, 2004 - medscape.com Ongoing studies and current reports have focused on the role of
hyperinsulinaemia and increased insulin resistance as major pathogenic factors
in the development of non-alcoholic steatohepatitis. [7,8] On the basis of ... Cited by 199 - Related articles - BL Direct - All 10 versions
- ►perioimplantelsalvador.com [PDF] BL Mealey, TW Oates - Journal of Periodontology, 2006 - Am Acad Periodontology Background: The purpose of this review is to provide the reader with practical
knowledge concerning the relationship between diabetes mellitus and periodontal
diseases. Over 200 articles have been published in the English literature ... Cited by 160 - Related articles - BL Direct - All 18 versions
- ►iiginc.org [PDF] - Free from Publisher J Medina, LI Fernández-Salazar, L García- … - Diabetes care, 2004 - Am Diabetes Assoc Nonalcoholic steatohepatitis (NASH) represents an advanced stage of fatty liver
disease developed in the absence of alcohol abuse. Its increasing prevalence in
western countries, the diagnostic difficulties by noninvasive tests, and ... Cited by 136 - Related articles - All 8 versions
- ►nursing2008.com RS Hundal, SE Inzucchi - Drugs, 2003 - ingentaconnect.com Metformin, a biguanide, has been available in the US for the treatment of type
Abstract 2 diabetes mellitus for nearly 8 years. Over this period of time, it
has become the most widely prescribed antihyperglycaemic agent. Its ... Cited by 112 - Related articles - BL Direct - All 7 versions
- ►endojournals.org P Marchetti, S Del Guerra, L Marselli, R Lupi, … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Several properties of pancreatic ß-cells in type 2 diabetes (T2D) were studied
by using islets isolated from T2D subjects. Moreover, because metformin has
protective effects on nondiabetic ß-cells exposed to high glucose or free ... Cited by 92 - Related articles - BL Direct - All 5 versions
JB Buse, DC Klonoff, LL Nielsen, X Guan, … - Clinical therapeutics, 2007 - Elsevier For this interim analysis, data were pooled from patients who completed 1 of
three 30-week, multicenter, double-blind, placebo-controlled trials and their
open-label extensions. In the initial trials, subjects were randomized to ... Cited by 91 - Related articles - All 3 versions