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Scholar Results 1 - 10 of about 133 citing Molldrem: Antithymocyte globulin for treatment of the bone marrow failure associated with.... (0.09 sec) 

Myelodysplastic syndrome


WK Hofmann, HP Koeffler, 2004 - Annual Reviews
During the past 15 years, important progress has been made in the understanding
of the biology and prognosis of myelodysplastic syndrome (MDS). MDS is a clonal
disorder characterized by ineffective hematopoiesis, which can lead to ...
Cited by 84 - Related articles - BL Direct - All 10 versions

A simple method to predict response to immunosuppressive therapy in patients with …

- bloodjournal.org
Y Saunthararajah, R Nakamura, R Wesley, QJ … - Blood, 2003 - Am Soc Hematology
Immunosuppression with antithymocyte globulin (ATG) or cyclosporine (CSA) can be
used to treat the cytopenia associated with myelodysplastic syndrome (MDS).
Previously, we identified HLA-DR15, younger age, and shorter duration of ...
Cited by 80 - Related articles - BL Direct - All 5 versions

The myelodysplastic syndromes: diagnosis and treatment

- mayoclinicproceedings.com
DP Steensma, JM Bennett - Mayo Clinic Proceedings, 2006 - mayoclinicproceedings.com
The myelodysplastic syndromes (MDSs) are common, acquired, clinically
challenging hematologic conditions that are characterized by bone marrow failure
and a risk of progression to acute leukemia. These disorders can arise de ...
Cited by 68 - Related articles - BL Direct - All 8 versions

Myelodysplastic syndrome

- hematologylibrary.org
G Mufti, AF List, SD Gore, AYL Ho - Hematology, 2003 - asheducationbook.hematologylibrary.org
The last decade has witnessed a multistep evolution in the understanding of the
natural history, clinical manifestations, and some of the molecular mechanisms
that underlie the ineffective hematopoiesis and leukemic transformation in ...
Cited by 63 - Related articles - All 5 versions

Antithymocyte globulin has limited efficacy and substantial toxicity in unselected anemic …

- bloodjournal.org [PDF] 
DP Steensma, A Dispenzieri, SB Moore, G … - Blood, 2003 - Am Soc Hematology
The myelodysplastic syndrome (MDS) includes a heterogeneous group of marrow
disorders characterized by ineffective hematopoi- esis and a variable risk of
leukemic transformation. Because most patients with MDS are diagnosed after ...
Cited by 55 - Related articles - All 6 versions

A prospective, randomised, phase II study of horse antithymocyte globulin vs rabbit …


M Stadler, U Germing, KO Kliche, KM Josten, … - Leukemia, 2004 - nature.com
Immunosuppression has recently been proposed for low-risk myelodysplastic
syndromes (MDS) to reverse bone marrow failure by inhibiting intramedullary
secretion of proapoptotic cytokines. We treated 35 MDS patients (24 ...
Cited by 52 - Related articles - All 3 versions

Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by …

- hematologylibrary.org - Free from Publisher
EM Sloand, L Mainwaring, M Fuhrer, S … - Blood, 2005 - bloodjournal.hematologylibrary.org
Clinical observations and experimental evidence link bone marrow failure in
myelodysplastic syndrome (MDS) with a T cell–dominated autoimmune process.
Immunosuppressive therapy is effective in improving cytopenias in selected ...
Cited by 47 - Related articles - BL Direct - All 6 versions

T-cell large granular lymphocyte leukemia and related disorders

- alphamedpress.org
MG Rose, N Berliner - The Oncologist, 2004 - AlphaMed Press
T-cell large granular lymphocyte (LGL) leukemia is a clonal proliferation of
cytotoxic T cells, which causes neutropenia, anemia, and/or thrombocytopenia.
This condition is often associated with autoimmune disorders, especially ...
Cited by 44 - Related articles - All 12 versions

Novel therapies for myelodysplastic syndromes


S Faderl, HM Kantarjian - CA A Cancer Journal for Clinicians - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 41 - Related articles - BL Direct - All 3 versions

Myelodysplasic syndromes: a comprehensive review


DVT Catenacci, GJ Schiller - Blood reviews, 2005 - Elsevier
Myelodysplastic syndromes (MDS) are a set of oligoclonal disorders of
hematopoietic stem cells characterized by ineffective hematopoiesis that
manifest clinically as anemia, neutropenia, and/or thrombocytopenia of ...
Cited by 41 - Related articles - All 8 versions


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