- ►chestpubs.org J Ansell, J Hirsh, E Hylek, A Jacobson, M … - Chest, 2008 - chestjournal.chestpubs.org This article concerning the pharmacokinetics and pharmacodynamics of vitamin K
antagonists (VKAs) is part of the American College of Chest Physicians
Evidence-Based Clinical Practice Guidelines (8th Edition). It describes the ... Cited by 892 - Related articles - BL Direct - All 21 versions
- ►ahajournals.org J Hirsh, V Fuster, J Ansell, JL Halperin - Journal of the American College of Cardiology, 2003 - Elsevier Warfarin, a coumarin derivative, produces an anticoagulant effect by interfering
with the cyclic interconversion of vitamin K and its 2,3 epoxide (vitamin K
epoxide). Vitamin K is a cofactor for the carboxylation of glutamate ... Cited by 357 - Related articles - BL Direct - All 20 versions
RI Baker, PB Coughlin, AS Gallus, PL Harper … - Medical Journal of Australia, 2004 - mja.com.au Warfarin pharmacokinetics and pharmacodynamics Warfarin and other coumarin
anticoagulants act by inhibiting the synthesis of functional vitamin K-dependent
coagulation factors II, VII, IX and X.4 Anticoagulants have no direct ... Cited by 92 - Related articles - View as HTML - BL Direct - All 16 versions
- ►ahajournals.org JN Goldstein, SH Thomas, V Frontiero, A … - Stroke, 2006 - Am Heart Assoc Methods— Consecutive patients with warfarin-related ICH presenting to an urban
tertiary care hospital from 1998 to 2004 were prospectively captured in a
database. ED records were retrospectively reviewed for dose and timing of ... Cited by 53 - Related articles - All 11 versions
- ►epdoc.net [PDF] A Lubetsky, H Yonath, D Olchovsky, R … - Archives of Internal Medicine, 2003 - archinte.highwire.org Methods The study was a prospective randomized controlled trial of consecutive
patients presenting with excessive anticoagulation without major bleeding.
Patients with a baseline international normalized ratio (INR) of 6 to 10 (n ... Cited by 50 - Related articles - BL Direct - All 6 versions
F Dentali, W Ageno, M Crowther - Journal of Thrombosis and Haemostasis, 2006 - interscience.wiley.com Summary. Background: An excessive anticoagulant effect because of coumarins is
frequently encountered. Objective: To review available literature on the
management of warfarin-associated coagulopathy and to propose ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►muhealth.org [PDF] KJ DeZee, WT Shimeall, KM Douglas, NM … - Archives of Internal Medicine, 2006 - archinte.highwire.org Methods The MEDLINE, EMBASE, and Cochrane Library databases were searched
(without language restrictions) for articles published between January 1985 and
September 2004. Randomized controlled trials or prospective, nonrandomized ... Cited by 27 - Related articles - BL Direct - All 5 versions
- ►onlinejacc.org DA Garcia, S Regan, M Crowther, EM Hylek - Journal of the American College of Cardiology, 2006 - Elsevier For warfarin-treated patients, the risk of bleeding increases as the INR rises,
particularly if the INR exceeds 4. The 30-day risk of hemorrhage among
outpatients with excessively prolonged INR values is unknown. Cited by 21 - Related articles - BL Direct - All 23 versions
SE Pass, RW Simpson - American Journal of Health-System Pharmacy, 2004 - ASHP S TEVEN E. P ASS , P HARM .D., BCPS, is Clinical Pharmacy Practitioner—
Critical Care, University Hospital (UH), Cincinnati, OH, and Assis- tant
Professor of Clinical Pharmacy Practice, University of Cincin- nati College ... Cited by 22 - Related articles - BL Direct - All 10 versions
- ►canadianmedicaljournal.ca SE Wilson, HG Watson, MA Crowther - Canadian Medical Association Journal, 2004 - canadianmedicaljournal.ca ASYMPTOMATIC ELEVATION OF THE INTERNATIONAL normalized ratio (INR) is a common
problem associated with hemorrhage. Evidence from randomized controlled trials
supports the use of low-dose oral vitamin K therapy as a treatment that ... Cited by 17 - Related articles - BL Direct - All 12 versions
