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Scholar Results 1 - 10 of about 196 citing Krantz: Torsade de pointes associated with very-high-dose methadone. (0.10 sec) 

Interindividual variability of the clinical pharmacokinetics of methadone: implications for …

- ireta.org [PDF] 
CB Eap, T Buclin, P Baumann - Clinical pharmacokinetics, 2002 - ingentaconnect.com
Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . 1153 1. Chirality and Pharmacodynamics . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1155 2. ...
Cited by 192 - Related articles - BL Direct - All 8 versions

QTc interval prolongation associated with intravenous methadone

- capitalhospice.org [PDF] 
CA Kornick, MJ Kilborn, J Santiago-Palma, G … - Pain, 2003 - Elsevier
Numerous medications prolong the rate-corrected QT (QTc) interval and induce
arrhythmias by blocking ionic current through cardiac potassium channels
composed of subunits expressed by the human ether-a-go-go-related gene ...
Cited by 85 - Related articles - All 10 versions

Dose-related effects of methadone on QT prolongation in a series of patients with torsade de …


MJ Krantz, IB Kutinsky, AD Robertson, PS … - Pharmacotherapy, 2003 - PPI
A prolonged corrected QT (QTc) interval is an established marker of arrhythmia
risk, primarily for a form of polymorphic ventricular tachycardia known as
torsade de pointes. Many anti- arrhythmic drugs exhibit dose-related ...
Cited by 81 - Related articles - BL Direct - All 6 versions

QT prolongation and torsades de pointes in patients infected with human immunodeficiency …


M Gil, M Sala, I Anguera, O Chapinal, M … - The American journal of cardiology, 2003 - Elsevier
The introduction of highly active antiretroviral therapy for the treatment of
human immunodeficiency virus (HIV) infection has increased drug interactions due
to the induction and/or inhibition of cytochrome P450. Pharmacokinetic ...
Cited by 71 - Related articles - All 10 versions

Cardiovascular manifestations of substance abuse: part 2: alcohol, amphetamines, heroin, …


WH Frishman, A Del Vecchio, S Sanal, A … - Heart Disease, 2003 - pt.wkhealth.com
The abuse of alcohol is associated with chronic cardiomyopathy, hypertension,
and arrhythmia. Abstinence or using alcohol in moderation can reverse these
cardiovascular problems. Alcohol is also distinguished among the substances ...
Cited by 73 - Related articles - BL Direct - All 5 versions

Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency …

- pharmacoclean.ch [PDF] 
GB Ehret, C Voide, M Gex-Fabry, J Chabert, D … - Archives of Internal Medicine, 2006 - archinte.highwire.org
Methods We performed a systematic, retrospective study comparing active or
former intravenous drug users receiving methadone and those not receiving
methadone among all patients hospitalized over a 5-year period in a ...
Cited by 70 - Related articles - BL Direct - All 8 versions

Clinical relevance and management of drug-related QT interval prolongation


MA Crouch, L Limon, AT Cassano - Pharmacotherapy, 2003 - PPI
Michael A. Crouch, Pharm.D., Lynn Limon, Pharm.D., and Angela T. Cassano,
Pharm.D. ... Much attention recently has focused on drugs that prolong the QT
interval, potentially leading to fatal cardiac dysrhythmias (eg, torsade de ...
Cited by 66 - Related articles - BL Direct - All 5 versions

Treating opioid dependence: growing implications for primary care


MJ Krantz, PS Mehler - Archives of internal medicine, 2004 - Am Med Assoc
Almost 3 million Americans have abused heroin. The most effective treatment for
this concerning epidemic is opioid replacement therapy. Although, from a
historical perspective, acceptance of this therapy has been slow, growing ...
Cited by 55 - Related articles - BL Direct - All 4 versions

QT prolongation and torsades de pointes among methadone users: reports to the FDA …


EC Pearson, RL Woosley - Pharmacoepidemiology and drug safety, 2005 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 53 - Related articles - BL Direct - All 4 versions

QTc interval prolongation in patients on long-term methadone maintenance therapy


I Maremmani, M Pacini, C Cesaroni, M … - Eur Addict Res, 2005 - content.karger.com
Icro Maremmani, MD Department of Psychiatry, NFB, 'Santa Chiara', University
Hospital University of Pisa Via Roma 67, IT–56100 Pisa (Italy) Tel. +39
050993045, Fax +39 05021581, E-Mail maremman@psico.med.unipi.it
Cited by 47 - Related articles - BL Direct - All 4 versions


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