J Clardy, C Walsh - Nature, 2004 - openwetware.org Natural products have inspired chemists and physicians for millennia. Their rich
structural diversity and complexity has prompted synthetic chemists to produce
them in the laboratory, often with therapeutic applications in mind, and ... Cited by 182 - Related articles - View as HTML - BL Direct - All 22 versions
N Fischel-Ghodsian - Pharmacogenomics, 2005 - Future Medicine Ototoxicity is the major irreversible toxicity of aminoglycosides, and it occurs
both in a dose-dependent and idiosyncratic fashion. The idiosyncratic pathway is
presumably due to genetic predispositions, and an inherited mutation in the ... Cited by 100 - Related articles - BL Direct - All 9 versions
- ►hematologylibrary.org [PDF] A Dispenzieri, MQ Lacy, JA Katzmann, SV … - Blood, 2006 - bloodjournal.hematologylibrary.org . Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ... Cited by 78 - Related articles - BL Direct - All 9 versions
- ►oxfordjournals.org RJ Amato - Annals of oncology, 2005 - Eur Soc Med Oncology A search of the Medline database and ASCO 2003 conference proceedings was
conducted to identify clinical trials currently underway using single-agent
therapy for renal cell carcinoma (RCC). Combination trials were identified ... Cited by 69 - Related articles - All 8 versions
- ►hematologylibrary.org M Koptyra, R Falinski, MO Nowicki, T Stoklosa … - Blood, 2006 - bloodjournal.hematologylibrary.org BCR/ABL kinase mutations appear to be the most frequent cause of acquired
resistance to IM; resistant cells also may exhibit genomic amplification of
nonmutated BCR/ABL and BCR/ABL independence due to overexpression of LYN ... Cited by 64 - Related articles - BL Direct - All 6 versions
FR Lashley, 2005 - books.google.com S^^ 1 Felissa R. Lashley, RN, PhD, FAAN, FACMG (formerly Felissa L. Cohen), is
^1 ^^ I Dean and Professor of the College of Nursing at Rutgers, The State
University ^L 1 of New Jersey. Prior to that she was Dean and Professor of ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►brimr.org [PDF] R Roskoski - Biochemical and Biophysical Research …, 2003 - Elsevier STI-571 (imatinib, Gleevec, Glivec, CGP 57148) is an inhibitor of the Abl group
of protein-tyrosine kinases. One of these enzymes, the Bcr-Abl oncoprotein,
results from the fusion of the BCR and ABL genes that result from the ... Cited by 56 - Related articles - All 11 versions
- ►mcponline.org DS Gembitsky, K Lawlor, A Jacovina, M … - Molecular & Cellular Proteomics, 2004 - ASBMB Reversible protein phosphorylation is a key regulatory process in all living
cells. Deregulation of modification control mechanisms, especially in the case
of tyrosine, may lead to malignant transformation and disease. ... Cited by 54 - Related articles - BL Direct - All 3 versions
AJ Rai, DW Chan - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2004 - interscience.wiley.com Abstract: Cancer proteomics is an exciting field that is witnessing many new
developments in recent years. It is hoped that these advances will result in
decreased cancer death rates, which have not declined dramatically in the ... Cited by 50 - Related articles - BL Direct - All 5 versions
L Asnaghi, A Calastretti, A Bevilacqua, I D' … - Oncogene, 2004 - nature.com The serine/threonine kinase mTOR, the major sensor of cell growth along the
PI3K/Akt pathway, can be activated by agents acting on microtubules. Damaged
microtubules induce phosphorylation of the Bcl-2 protein and lower the ... Cited by 43 - Related articles - BL Direct - All 5 versions