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Scholar Results 1 - 10 of about 67 citing Du: Discrepancy between consensus recommendations and actual community use of adjuvant chemothera.... (0.07 sec) 

Capecitabine as adjuvant treatment for stage III colon cancer

- shouxi.net
C Twelves, A Wong, MP Nowacki, M Abt, H … - New England Journal of Medicine, 2005 - content.nejm.org
Methods We randomly assigned a total of 1987 patients with resected stage III
colon cancer to receive either oral capecitabine (1004 patients) or bolus
fluorouracil plus leucovorin (Mayo Clinic regimen; 983 patients) over a ...
Cited by 360 - Related articles - All 12 versions

Oral capecitabine as an alternative to iv 5-fluorouracil-based adjuvant therapy for colon cancer …

- oxfordjournals.org
W Scheithauer, J McKendrick, S Begbie, M … - Annals of oncology, 2003 - Eur Soc Med Oncology
Oral capecitabine achieves a superior response rate with an improved safety
profile compared with bolus 5-fluorouracil–leucovorin (5-FU/LV) as first-line
treatment for patients with metastatic colorectal cancer. We report here ...
Cited by 119 - Related articles - All 8 versions

Adjuvant chemotherapy in older and younger women with lymph node-positive breast …


HB Muss, S Woolf, D Berry, C Cirrincione, … - JAMA, 2005 - Am Med Assoc
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Cited by 112 - Related articles - All 4 versions

Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year …

- ascopubs.org
L Talarico, G Chen, R Pazdur - Journal of Clinical Oncology, 2004 - jco.ascopubs.org
PATIENTS AND METHODS: This study involved retrospective analyses of demographic
data of cancer patients enrolled onto registration trials. The data on 28,766
cancer patients from 55 registration trials were analyzed according to age ...
Cited by 96 - Related articles - BL Direct - All 8 versions

Chemotherapy and cardiotoxicity in older breast cancer patients: a population-based study

- ascopubs.org
JJ Doyle, AI Neugut, JS Jacobson, VR Grann … - Journal of Clinical Oncology, 2005 - jco.ascopubs.org
RESULTS: Of 31,748 women with stage I to III breast cancer, 5,575 (18%) received
chemotherapy. Chemotherapy was associated with younger age, fewer comorbidities,
hormone receptor negativity, multiple primary tumors, and advanced disease. ...
Cited by 70 - Related articles - All 11 versions

Disease-free survival advantage of weekly epirubicin plus tamoxifen versus tamoxifen alone as …

- jcojournal.org
P Fargeot, J Bonneterre, H Roche, A … - Journal of Clinical Oncology, 2004 - jcojournal.org
PATIENTS AND METHODS: A total of 338 patients were randomly assigned after
surgery to receive TAM 30 mg/d for 3 years (TAM, n = 164), or EPI 30 mg on days
1, 8, and 15 every 28 days for six cycles plus TAM 30 mg/d for 3 years ...
Cited by 62 - Related articles - BL Direct - All 10 versions

Breast cancer treatment of older women in integrated health care settings

- ascopubs.org
SM Enger, SS Thwin, DSM Buist, T Field, F … - Journal of Clinical Oncology, 2006 - jco.ascopubs.org
RESULTS: Women 75 years of age or older and women with higher comorbidity
indices were more likely to receive nonstandard primary tumor therapy, to not
receive axillary lymph node dissection, and to not receive radiation ...
Cited by 56 - Related articles - All 9 versions

Adjuvant chemotherapy and survival in older women with hormone receptor-negative breast …

- ascopubs.org
EB Elkin, A Hurria, N Mitra, D Schrag, KS … - Journal of Clinical Oncology, 2006 - jco.ascopubs.org
RESULTS: A total of 1,711 (34%) of 5,081 women with HR-negative breast cancer
received chemotherapy within 6 months of cancer diagnosis. Chemotherapy use
decreased with increasing age and comorbidity, and increased with year of ...
Cited by 52 - Related articles - All 8 versions

The integral role of clinical research in clinical care


SM Grunberg, WT Cefalu - The New England journal of medicine, 2003 - nejm.highwire.org
Does acceptance of the principle of clinical equipoise require us to abandon our
Hippocratic responsibilities to our patients? In the interest of maintaining the
ethical principles of beneficence and nonmaleficence, it is actually easier ...
Cited by 34 - Related articles - BL Direct - All 5 versions

Differences in management of older women influence breast cancer survival: results from …


S Eaker, PW Dickman, L Bergkvist, L Holmberg … - PLoS Medicine, 2006 - pubmedcentral.nih.gov
1 Department of Surgery, University Hospital of Uppsala and Regional Oncologic
Centre, Uppsala, Sweden, 2 Department of Medical Epidemiology and Biostatistics,
Karolinska Institutet, Stockholm, Sweden, 3 Department of Surgery, Centre ...
Cited by 27 - Related articles - BL Direct - All 7 versions


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