KM Langa, NL Foster, EB Larson - Jama, 2004 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do
to make your experience on this site better. ... Context The prevalence of ... Cited by 114 - Related articles - BL Direct - All 6 versions
- ►sciencesignaling.org JL Kennedy, LA Farrer, NC Andreasen, R … - Science's STKE, 2003 - stke.sciencemag.org Abstract: Genetic factors play a major role in the etiology of adult-onset
neurodegenerative and neuropsychiatric disorders. Several highly penetrant genes
have been cloned for rare, autosomal-dominant, early-onset forms of ... Cited by 112 - Related articles - BL Direct - All 18 versions
- ►endojournals.org VC Russo, PD Gluckman, EL Feldman, GA … - Endocrine Reviews, 2005 - Endocrine Soc In recent years, much interest has been devoted to defining the role of the IGF
system in the nervous system. The ubiquitous IGFs, their cell membrane
receptors, and their carrier binding proteins, the IGFBPs, are expressed ... Cited by 98 - Related articles - BL Direct - All 4 versions
E Carro, I Torres-Aleman - European journal of pharmacology, 2004 - Elsevier Cellular and molecular processes leading to abnormal accumulation of β amyloid
in the brain are slowly being uncovered. A potential involvement of insulin and
insulin-like growth factor I (IGF-I) in this plausible pathogenic process ... Cited by 91 - Related articles - All 6 versions
- ►oxfordjournals.org HW Klafki, M Staufenbiel, J Kornhuber, J … - Brain, 2006 - Oxford Univ Press Alzheimer's disease is an age-related progressive neurodegenerative disorder
with an enormous unmet medical need. It is the most common form of dementia
affecting 5% of adults over 65 years. In view of our ageing society the ... Cited by 80 - Related articles - BL Direct - All 8 versions
- ►umt.edu [PDF] JJ Anderson, G Holtz, PP Baskin, M Turner, … - Biochemical pharmacology, 2005 - Elsevier A primary pathological feature of Alzheimer's disease is β-amyloid
(Aβ)-containing plaques in brain and cerebral vasculature. Reductions in the
formation of Aβ peptides by γ-secretase inhibitors may be a viable ... Cited by 58 - Related articles - All 4 versions
T Kihara, H Sawada, T Nakamizo, R Kanki, H … - Biochemical and biophysical research communications, 2004 - Elsevier Galantamine is a plant alkaloid that is used in the treatment of Alzheimer's
disease. We have studied the effects of galantamine on β-amyloid-enhanced
glutamate toxicity using primary rat cultured cortical neurons. Nicotine ... Cited by 49 - Related articles - All 5 versions
AM Bertoli-Avella, BA Oostra, P Heutink - Human genetics, 2004 - Springer Abstract Alzheimer's disease (AD), the most common type of dementia, and
Parkinson's disease (PD), the most common movement disorder, are both
neurodegenerative adult-onset diseases characterized by the progressive ... Cited by 34 - Related articles - BL Direct - All 4 versions
EW Gregg, A Brown - Clinical Diabetes, 2003 - Am Diabetes Assoc The increase in diabetes among the elderly is concerning because, in addition to
the wide range of traditional diabetes complications (including acute
hyperglycemic and hypoglycemic events and vascular complications that may ... Cited by 24 - Related articles - BL Direct - All 2 versions
A Huber, G Stuchbury, A Burkle, J Burnell, G … - Current pharmaceutical design, 2006 - ingentaconnect.com Abstract: One of the major age-related damaging agents are reactive oxygen
species (ROS). The brain is more vulnerable to oxidative stress than other
organs as concomitant low activity and capacity of antioxidative protection ... Cited by 22 - Related articles - BL Direct - All 5 versions
