- ►shouxi.net A Pietrangelo - The New England journal of medicine, 2004 - nejm.highwire.org In the few years since the discovery of the HFE gene, our understanding of
hereditary hemochromatosis and of human iron metabolism in general has become
much more complete (Figure 1). We know that mutations in other genes that ... Cited by 492 - Related articles - BL Direct - All 15 versions
- ►hemocromatosis.es [PDF] PC Adams, DM Reboussin, JC Barton, CE … - The New England journal of medicine, 2005 - nejm.highwire.org Results Of the 99,711 participants, 299 were homozygous for the C282Y mutation.
The estimated prevalence of C282Y homozygotes was higher in non-Hispanic whites
(0.44 percent) than in Native Americans (0.11 percent), Hispanics (0.027 ... Cited by 206 - Related articles - All 15 versions
- ►hematologylibrary.org E Beutler, AV Hoffbrand, JD Cook - Hematology, 2003 - asheducationbook.hematologylibrary.org In Section I, Dr. Beutler also discusses the types of hemochromatosis that exist
as acquired and as hereditary forms. Acquired hemochromatosis occurs in patients
with marrow failure, particularly when there is active ineffective ... Cited by 101 - Related articles - All 7 versions
J Waalen, BG Nordestgaard, E Beutler - Best Practice & Research Clinical Haematology, 2005 - Elsevier Since its original description as a rare disease of iron overload resulting in
liver disease, diabetes mellitus, and bronzing of the skin ('bronze diabetes'),
hereditary hemochromatosis has undergone several redefinitions leading to ... Cited by 102 - Related articles - BL Direct - All 17 versions
- ►asnjournals.org DW Coyne, T Kapoian, W Suki, AK Singh, JE … - Journal of the American Society of Nephrology, 2007 - Am Soc Nephrol Few data exist to guide treatment of anemic hemodialysis patients with high
ferritin and low transferrin saturation (TSAT). The Dialysis Patients' Response
to IV Iron with Elevated Ferritin (DRIVE) trial was designed to evaluate ... Cited by 81 - Related articles - BL Direct - All 6 versions
LW Powell, JL Dixon, GA Ramm, DM Purdie, … - Archives of Internal Medicine, 2006 - Am Med Assoc Background Hemochromatosis in white subjects is mostly due to homozygosity for
the common C282Y substitution in HFE. Although clinical symptoms are preventable
by early detection of the genetic predisposition and prophylactic ... Cited by 72 - Related articles - All 4 versions
PC Adams - Clinics in liver disease, 2004 - Elsevier A challenge in this field is that the term “hemochromatosis” means different
things to different physicians. To some, hemochromatosis is synonymous with iron
overload, and yet there are a growing number of cases of iron overload with ... Cited by 60 - Related articles - BL Direct - All 6 versions
A Pietrangelo - Hepatology, 2007 - interscience.wiley.com This review acknowledges the recent and dramatic advancement in the field of
hemochromatosis and highlights the surprising analogies with a prototypic
endocrine disease, diabetes. The term hemochromatosis should refer to a ... Cited by 52 - Related articles - BL Direct - All 3 versions
A Qaseem, M Aronson, N Fitterman, V Snow, … - Annals of internal medicine, 2005 - Am Coll Physicians Hereditary hemochromatosis is a genetic disorder of iron metabolism. Diagnosis
of hereditary hemochromatosis is usually based on a combination of various
genetic or phenotypic criteria. Decisions regarding screening are difficult ... Cited by 40 - Related articles - BL Direct - All 9 versions
- ►annals.org [PDF] B Schmitt, RM Golub, R Green - Annals of internal medicine, 2005 - Am Coll Physicians Background: Therapeutic phlebotomy for hereditary hemochro- matosis is
relatively safe and presumably efficacious when offered before cirrhosis
develops, so screening primary care patients is of substantial interest. ... Cited by 38 - Related articles - BL Direct - All 5 versions
