M De Martinis, C Franceschi, D Monti, L … - FEBS letters, 2005 - Elsevier Immunosenescence is the consequence of the continuous attrition caused by
chronic antigenic stress. The most important characteristics of immunosenescence
(accumulation of memory and effector T cells, reduction of naive T cells, ... Cited by 75 - Related articles - All 10 versions
- ►oxfordjournals.org G Gong, O Kosoko-Lasaki, GR Haynatzki, MR … - Human Molecular Genetics, 2004 - Oxford Univ Press Primary open-angle glaucoma (POAG) is a complex disease with unknown causes.
However, in the past decade, POAG has been linked to six chromosomal regions, of
which the gene MYOC encoding myocilin and the gene OPTN encoding optineurin ... Cited by 64 - Related articles - BL Direct - All 5 versions
KR Chien, G Karsenty - Cell, 2005 - Elsevier Is human aging inextricably linked to longevity? With regard to this query,
where you stand may depend on where you sit. For the scientist seated at the
bench, the answer may be based on seminal studies in invertebrate model ... Cited by 43 - Related articles - All 19 versions
JB Hjelmborg, I Iachine, A Skytthe, JW … - Human Genetics, 2006 - Springer Abstract There is an intense search for longevity genes in both animal models
and humans. Human family studies have indicated that a modest amount of the
overall variation in adult lifespan (approximately 20–30%) is accounted ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org PB Gorelick - Stroke, 2005 - Am Heart Assoc Conclusions— Because vascular risk factors may have negative effects on brain
structure and cognitive function, and because vascular risk factors may be
present in midlife or possibly earlier, we may need to develop long-term ... Cited by 41 - Related articles - All 7 versions
- ►bmj.com D Lio, G Candore, A Crivello, L Scola, G … - British Medical Journal, 2004 - jmg.bmj.com Patients with atherosclerosis have a proinflammatory genotype, and tight control
of inflammatory reactions might decrease the incidence of atherosclerosis. Gene
polymorphisms for proinflammatory cytokines seem to contribute considerably ... Cited by 35 - Related articles - BL Direct - All 7 versions
DF Terry, MJ Pencina, RS Vasan, JM Murabito … - Journal of the American Geriatrics Society, 2005 - medscape.com Prior research has established that health-related behaviors and genetic
influences play important roles in survival to exceptional old age. [1-3]
Studies of centenarians and their offspring have demonstrated that the ... Cited by 34 - Related articles - BL Direct - All 8 versions
G Candore, CR Balistreri, F Listi, MP … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2006 - interscience.wiley.com Abstract: In this article we discuss relevant data on aging, longevity, and
gender with particular focus on inflammation gene polymorphisms which could
affect an individual's chance to reach the extreme limit of human life. The ... Cited by 25 - Related articles - BL Direct - All 4 versions
RM Green, 2007 - books.google.com A Caravan book. For more information, visit www.caravanbooks.org. The quotation
beginning chapter 5 is from page 3 of Brave New World by Aldous Huxley, 1st
Perennial Classics ed. (New York: HarperCollins, Harper Perennial, 1998). ... Cited by 9 - Related articles - All 2 versions
F Marchegiani, M Marra, F Olivieri, M … - Rejuvenation Research, 2008 - liebertonline.com The increasing longevity of the population, one of the most important issues
throughout the planet, is a very complex phenomenon (trait), likely resulting
from a variety of environmen- tal determinants interacting with and ... Cited by 9 - Related articles - BL Direct - All 3 versions
