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Scholar Results 1 - 10 of about 64 citing Snowdon: Healthy aging and dementia: findings from the Nun Study. (0.09 sec) 

Neurovascular mechanisms of Alzheimer's neurodegeneration


BV Zlokovic - Trends in neurosciences, 2005 - Elsevier
In contrast to traditional neuroncentric views of Alzheimer's disease (AD),
recent findings indicate that neurovascular dysfunction contributes to cognitive
decline and neurodegeneration in AD. Here, I propose the neurovascular ...
Cited by 196 - Related articles - All 6 versions

Postsynaptic receptor trafficking underlying a form of associative learning


S Rumpel, J LeDoux, A Zador, R Malinow - Science, 2005 - sciencemag.org
Page 1. DOI: 10.1126/science.1103944 , 83 (2005); 308 Science et al. Simon Rumpel,
Form of Associative Learning Postsynaptic Receptor Trafficking Underlying a ...
Cited by 157 - Related articles - All 8 versions

A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease

- alzforum.org [PDF] 
RH Swerdlow, SM Khan - Medical hypotheses, 2004 - Elsevier
Alzheimer's disease (AD) includes etiologically heterogenous disorders
characterized by senile or presenile dementia, extracellular amyloid protein
aggregations containing an insoluble amyloid precursor protein derivative, ...
Cited by 76 - Related articles - All 21 versions

Clinical trials in mild cognitive impairment: lessons for the future

- nih.gov
V Jelic, M Kivipelto, B Winblad - British Medical Journal, 2006 - jnnp.bmj.com
Mild cognitive impairment (MCI) is an operational definition for a cognitive
decline in individuals with a greater risk of developing dementia. The amnestic
subtype of MCI is of particular interest because these individuals most ...
Cited by 73 - Related articles - BL Direct - All 7 versions

Increased hippocampal plaques and tangles in patients with Alzheimer disease with a …


MA Rapp, M Schnaider-Beeri, HT Grossman, M … - Archives of general psychiatry, 2006 - Am Med Assoc
Context The hallmark pathological changes in Alzheimer disease (AD) are abundant
plaque and tangle formation, especially in the temporal lobes and hippocampus.
Although there is increasing evidence that major depression may interact ...
Cited by 60 - Related articles - BL Direct - All 4 versions

William M. Feinberg lecture: cognitive vitality and the role of stroke and cardiovascular …

- ahajournals.org
PB Gorelick - Stroke, 2005 - Am Heart Assoc
Conclusions— Because vascular risk factors may have negative effects on brain
structure and cognitive function, and because vascular risk factors may be
present in midlife or possibly earlier, we may need to develop long-term ...
Cited by 41 - Related articles - All 7 versions

[PDF] Dementia and its implications for public health


DP Chapman, SM Williams, TW Strine, RF … - Prev Chronic Dis, 2006 - icaa.cc
Introduction With the aging of the US population, a better under- standing of
the presentation and impact of dementia is essential to the future of public
health. Dementia refers not to a single disorder but to a number of ...
Cited by 25 - Related articles - View as HTML - All 10 versions

Is aging part of Alzheimer's disease, or is Alzheimer's disease part of aging?


RH Swerdlow - Neurobiology of aging, 2007 - Elsevier
For 70 years after Alois Alzheimer described a disorder of tangle-and-plaque
dementia, Alzheimer's disease was a condition of the relatively young.
Definitions of Alzheimer's disease (AD) have, however, changed over the ...
Cited by 20 - Related articles - All 9 versions

Age-related changes in brain activation during a delayed item recognition task

- columbia.edu [PDF] 
E Zarahn, B Rakitin, D Abela, J Flynn, Y Stern - Neurobiology of Aging, 2007 - Elsevier
To test competing models of age-related changes in brain functioning (capacity
limitation, neural efficiency, compensatory reorganization, and
dedifferentiation), young (n = 40; mean age = 25.1 years) and elderly (n = ...
Cited by 19 - Related articles - All 16 versions

Tooth loss, dementia and neuropathology in the Nun Study

- jada-plus.com
PS Stein, M Desrosiers, SJ Donegan, JF … - The Journal of the American Dental Association, 2007 - jada-plus.com
Background. Numerous studies have linked dementia to the subsequent
deterioration of oral health. Few investigators, however, have examined oral
disease as a potential risk factor in the development of dementia. The ...
Cited by 20 - Related articles - BL Direct - All 9 versions


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