WJ Pichler, J Tilch - Allergy, 2004 - interscience.wiley.com Diagnosis of drug hypersensitivity is difficult, as an enormous amount of
different drugs can elicit various immune-mediated diseases with distinct
pathomechanism. The lymphocyte transformation test (LTT) measures the ... Cited by 136 - Related articles - BL Direct - All 4 versions
- ►stevensjohnsonsyndrome.org [PDF] JC Roujeau - Toxicology, 2005 - Elsevier Even though there are some overlapping or unclassifiable cases, it is important
for clinicians to recognize and categorize severe cutaneous adverse
reactions/SCAR (bullous fixed drug eruptions/bFDE, acute generalized ... Cited by 96 - Related articles - All 8 versions
A Romano, M Blanca, MJ Torres, A Bircher, W … - Allergy, 2004 - eaaci.net Nonimmediate manifestations (ie occurring more than 1 h after drug admin-
istration), particularly maculopapular and urticarial eruptions, are common
during b-lactam treatment. The mechanisms involved in most nonimmediate ... Cited by 85 - Related articles - View as HTML - BL Direct - All 6 versions
RS Gruchalla, M Pirmohamed - N Engl J Med, 2006 - woooootw.googlepages.com This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a
review of formal guidelines, when they exist. The article end with the ... Cited by 74 - Related articles - View as HTML - BL Direct - All 11 versions
- ►jimmunol.org P Schaerli, M Britschgi, M Keller, UC Steiner … - The Journal of Immunology, 2004 - Am Assoc Immnol It is unknown whether neutrophilic inflammations can be regulated by T cells.
This question was analyzed by studying acute generalized exanthematous
pustulosis (AGEP), which is a severe drug hypersensitivity resulting in ... Cited by 51 - Related articles - BL Direct - All 4 versions
P Camus, P Bonniaud, A Fanton, C Camus, N … - Clinics in chest medicine, 2004 - Elsevier An ever-increasing number of drugs (350+) can cause injury to the lung
parenchyma, upper and lower airways, pulmonary circulation, pleura, mediastinum,
lymph nodes, and neuromuscular system. Infiltrative lung disease (ILD) is ... Cited by 47 - Related articles - BL Direct - All 7 versions
FA Pereira, AV Mudgil, DM Rosmarin - Journal of the American Academy of Dermatology, 2007 - Elsevier Toxic epidermal necrolysis (TEN) is an unpredictable, life-threatening drug
reaction associated with a 30% mortality. Massive keratinocyte apoptosis is the
hallmark of TEN. Cytotoxic T lymphocytes appear to be the main effector ... Cited by 47 - Related articles - All 20 versions
G Zaccara, D Franciotta, E Perucca - Epilepsia, 2007 - zielinskifam.com Summary: Idiosyncratic drug reactions may be defined as ad- verse effects that
cannot be explained by the known mechanisms of action of the offending agent, do
not occur at any dose in most patients, and develop mostly unpredictably in ... Cited by 45 - Related articles - View as HTML - BL Direct - All 6 versions
- ►saeconsortium.org [PDF] C Lonjou, N Borot, P Sekula, N Ledger, L … - Pharmacogenetics and Genomics, 2008 - journals.lww.com Page 1. Original article 99 A European study of HLA-B in Stevens–Johnson syndrome
and toxic epidermal necrolysis related to five high-risk drugs ... Cited by 42 - Related articles - BL Direct - All 5 versions
G Kanny, W Pichler, M Morisset, P Franck, B … - The Journal of Allergy and Clinical Immunology, 2005 - Elsevier In addition to immediate reactions, late adverse reactions to iodinated contrast
media (ICM) were reported in 2% to 5% of patients exposed to ICM and, as a
consequence, have recently gained more attention. A few well-documented ... Cited by 41 - Related articles - All 21 versions
