C Lerman, C Jepson, EP Wileyto, LH Epstein, M … - Neuropsychopharmacology, 2005 - nature.com Although bupropion and nicotine replacement therapy (NRT) are efficacious
tobacco dependence treatments, there is substantial interindividual variability
in therapeutic response and most smokers relapse. Pharmacogenetics research ... Cited by 91 - Related articles - BL Direct - All 6 versions
- ►annals.org [PDF] L Ranney, C Melvin, L Lux, E McClain, KN … - Annals of Internal Medicine, 2006 - Am Coll Physicians Background: While smoking cessation interventions have been shown to work,
questions remain about how to increase their efficacy. ... Purpose: To examine
strategies for effective tobacco treatment in adults and special populations. Cited by 93 - Related articles - BL Direct - All 12 versions
- ►ascopubs.org C Lerman, F Patterson, W Berrettini - Journal of Clinical Oncology, 2005 - jco.ascopubs.org Despite almost two decades of intensive tobacco control efforts, nearly one
quarter of Americans continue to smoke. The two United States Food and Drug
Administration–approved medications used to treat tobacco dependence, ... Cited by 74 - Related articles - All 8 versions
- ►shouxi.net ET Moolchan, ML Robinson, M Ernst, JL … - Pediatrics, 2005 - Am Acad Pediatrics Objectives. To determine the safety and efficacy of the nicotine patch and gum
for adolescents who want to quit smoking. ... Design. Double-blind,
double-dummy, randomized, 3-arm trial with a nicotine patch (21 mg), ... Cited by 74 - Related articles - All 8 versions
V Malaiyandi, C Lerman, NL Benowitz, C … - Molecular Psychiatry, 2006 - nature.com We investigated the effect of slow metabolism of nicotine, predicted by CYP2A6
genotypes resulting in 50% activity, on baseline smoking behaviours and
treatment variables in an open-label nicotine replacement therapy (NRT) ... Cited by 66 - Related articles - BL Direct - All 3 versions
NL Benowitz, 2008 - nature.com Understanding the basic and clinical pharmacology of nicotine provides a basis
for improved prevention and treatment of tobacco addiction. Nicotine acts on
nicotinic cholinergic receptors in the brain to release dopamine and other ... Cited by 48 - Related articles - All 4 versions
C Lerman, R Tyndale, F Patterson, EP Wileyto … - Clinical Pharmacology & Therapeutics, 2006 - nature.com * This work was supported by a Transdisciplinary Tobacco Use Research Center
Grant from the National Cancer Institute and the National Institute on Drug
Abuse (P5084718); by the Abramson Cancer Center and Annenberg Public Policy ... Cited by 47 - Related articles - All 5 versions
- ►usl7.toscana.it [PDF] RA Schnoll, C Lerman - Expert Opin. Emerging Drugs, 2006 - informahealthcare.com Tobacco dependence remains the leading cause of death and disease in the US and
a major cause of mortality around the world, yet 1 out of 5 American adults
smoke and 1.3 billion adults smoke worldwide. Nicotine replacement ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►tobaccoprogram.org [PDF] J Foulds, J Foulds, MB Steinberg, J Foulds, … - Drug and Alcohol Review, 2006 - informahealthcare.com In the mid-1970s there were no effective pharmacological treatments for tobacco
dependence and very few behavioural scientists or pharmaceutical companies were
putting significant efforts into this area. Indeed, outside the tobacco ... Cited by 34 - Related articles - BL Direct - All 7 versions
