MS Donaldson - Nutrition Journal, 2004 - nutritionj.com It has been estimated that 30–40 percent of all cancers can be prevented by
lifestyle and dietary measures alone. Obesity, nutrient sparse foods such as
concentrated sugars and refined flour products that contribute to impaired ... Cited by 121 - Related articles - Cached - All 28 versions
- ►nih.gov Q Chen, MG Espey, MC Krishna, JB Mitchell, … - Proceedings of the National Academy of Sciences of …, 2005 - National Acad Sciences Human pharmacokinetics data indicate that iv ascorbic acid (ascorbate) in
pharmacologic concentrations could have an unanticipated role in cancer
treatment. Our goals here were to test whether ascorbate killed cancer ... Cited by 112 - Related articles - BL Direct - All 40 versions
- ►jbc.org H Lu, CL Dalgard, A Mohyeldin, T McFate, AS … - Journal of Biological Chemistry, 2005 - ASBMB Continuous hydroxylation of the HIF-1 transcription factor subunit by oxygen and
2-oxoglutarate-dependent dioxygenases promotes decay of this protein and thus
prevents the transcriptional activation of many genes involved in energy ... Cited by 87 - Related articles - BL Direct - All 6 versions
- ►nutrition.org Y Li, HE Schellhorn - Journal of Nutrition, 2007 - Am Soc Nutrition Vitamin C is required for collagen synthesis and biosynthesis of certain
hormones and recommended dietary intake levels are largely based these
requirements. However, to function effectively as an antioxidant (or a pro- ... Cited by 44 - Related articles - BL Direct - All 3 versions
H Hemilä, 2006 - ethesis.helsinki.fi Page 1. Do vitamins C and E affect respiratory infections ? Harri Hemilä Do vitamins
C and E affect respiratory infections ? Harri Hemilä 95% CI RR ... Cited by 36 - Related articles - View as HTML - All 3 versions
- ►nih.gov Q Chen, MG Espey, AY Sun, JH Lee, MC … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Ascorbate (ascorbic acid, vitamin C), in pharmacologic concentrations easily
achieved in humans by iv administration, selectively kills some cancer cells but
not normal cells. We proposed that pharmacologic ascorbate is a prodrug for ... Cited by 37 - Related articles - BL Direct - All 12 versions
- ►ecmaj.ca SJ Padayatty, HD Riordan, SM Hewitt, A Katz, … - Canadian Medical Association Journal, 2006 - Can Med Assoc Early clinical studies showed that high-dose vitamin C, given by intravenous and
oral routes, may improve symptoms and prolong life in patients with terminal
cancer. Double-blind placebo-controlled studies of oral vitamin C therapy ... Cited by 35 - Related articles - BL Direct - All 41 versions
- ►nih.gov Q Chen, MG Espey, AY Sun, C Pooput, KL Kirk … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Ascorbic acid is an essential nutrient commonly regarded as an antioxidant. In
this study, we showed that ascorbate at pharmacologic concentrations was a
prooxidant, generating hydrogen-peroxide-dependent cytotoxicity toward a ... Cited by 34 - Related articles - All 10 versions
- ►oxfordjournals.org C Fumeron, T Nguyen-Khoa, C Saltiel, M … - Nephrology Dialysis Transplantation, 2005 - ERA-EDTA Background. There is increasing evidence for the presence of oxidative stress
and vitamin C deficiency in dialysis patients. Limited data, however, are
available regarding the effects of vitamin C supplementation on oxidative ... Cited by 29 - Related articles - BL Direct - All 8 versions
W Zou, P Yue, N Lin, M He, Z Zhou, S Lonial, … - Clinical Cancer Research, 2006 - AACR Purpose: PS-341 (bortezomib, Velcade), the first proteasome inhibitor approved
by the Food and Drug Administration for the treatment of patients with relapsed
multiple myeloma, induces apoptosis in human cancer cell lines. Vitamin C ( ... Cited by 27 - Related articles - BL Direct - All 5 versions
