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Scholar Results 1 - 10 of about 122 citing Ghofrani: Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount.... (0.19 sec) 

Reversal of experimental pulmonary hypertension by PDGF inhibition

- nih.gov
RT Schermuly, E Dony, HA Ghofrani, S … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig
Progression of pulmonary hypertension is associated with increased proliferation
and migration of pulmonary vascular smooth muscle cells. PDGF is a potent
mitogen and involved in this process. We now report that the PDGF receptor ...
Cited by 208 - Related articles - BL Direct - All 11 versions

Acute oxygen-sensing mechanisms

- shouxi.net
EK Weir, J Lopez-Barneo, KJ Buckler, SL … - New England Journal of Medicine, 2005 - content.nejm.org
In this review we examine the remarkable mechanisms by which different organs
detect and respond to acute changes in oxygen tension. Specialized tissues that
sense the local oxygen tension include glomus cells of the carotid body, ...
Cited by 116 - Related articles - BL Direct - All 7 versions

Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension

- atsjournals.org
JP Richalet, P Gratadour, P Robach, I Pham, M … - American journal of respiratory and critical care …, 2005 - Am Thoracic Soc
Exposure to high altitude induces pulmonary hypertension that may lead to
life-threatening conditions. In a randomized, double-blind, placebo-controlled
study, the effects of oral sildenafil on altitude-induced pulmonary ...
Cited by 105 - Related articles - All 7 versions

Sildenafil in the treatment of Raynaud's phenomenon resistant to vasodilatory therapy


R Fries, K Shariat, H von Wilmowsky, M Bohm - Circulation, 2005 - Am Heart Assoc
From Klinik für Innere Medizin III (Kardiologie, Angiologie, Internistische
Intensivmedizin), Universitätsklinikum des Saarlandes, Homburg/Saar (RF, KS,
MB), and Klinik für Rheumatologie, Knappschaftskrankenhaus, Püttlingen ...
Cited by 99 - Related articles - All 10 versions

Anti-proliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery …

- atsjournals.org [PDF] 
J Wharton, JW Strange, GMO Moller, EJ … - American journal of respiratory and critical care …, 2005 - Am Thoracic Soc
Page 1. Anti-proliferative Effects of Phosphodiesterase Type 5 Inhibition
in Human Pulmonary Artery Cells. John Wharton1, Julian ...
Cited by 84 - Related articles - BL Direct - All 7 versions

Assessing and reducing the cardiac risk of noncardiac surgery

- ahajournals.org
A Auerbach, L Goldman - Circulation, 2006 - Am Heart Assoc
Accurate estimation of a patient's risk for postoperative cardiac events (eg,
myocardial infarction, unstable angina, ventricular tachycardia, pulmonary
edema, and death) after noncardiac surgery can guide allocation of clinical ...
Cited by 80 - Related articles - All 5 versions

Physiological aspects of high-altitude pulmonary edema

- physiology.org
P Bartsch, H Mairbaurl, M Maggiorini, ER … - Journal of Applied Physiology, 2005 - Am Physiological Soc
High-altitude pulmonary edema (HAPE) develops in rapidly ascending
nonacclimatized healthy individuals at altitudes above 3,000 m. An excessive
rise in pulmonary artery pressure (PAP) preceding edema formation is the ...
Cited by 78 - Related articles - All 6 versions

Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary …

- annals.org [PDF] 
M Maggiorini, HP Brunner-La Rocca, S Peth, M … - Annals of Internal Medicine, 2006 - Am Coll Physicians
Background: High-altitude pulmonary edema (HAPE) is caused by exaggerated
hypoxic pulmonary vasoconstriction associated with decreased bioavailability of
nitric oxide in the lungs and by impaired reabsorption of alveolar fluid.
Cited by 61 - Related articles - BL Direct - All 6 versions

Phosphodiesterase type 5 and high altitude pulmonary hypertension


AA Aldashev, BK Kojonazarov, TA Amatov, TM … - British Medical Journal, 2005 - thorax.bmj.com
Results: At 3 months, patients on sildenafil 25 mg 8 hourly (n = 9) had a
significantly (p = 0.018) lower mean PAP (–6.9 mm Hg) at the end of the dosing
interval than those on placebo (n = 8) (95% CI –12.4 to –1.3). The ...
Cited by 56 - Related articles - BL Direct - All 10 versions

The practice of travel medicine: guidelines by the Infectious Diseases Society of America

- hug-ge.ch [PDF] 
DR Hill, CD Ericsson, RD Pearson, JS … - Clinical Infectious Diseases, 2006 - UChicago Press
Featured in New York Times "Searching the Web for Flu Outbreaks" November 28,
2008 Using Internet Searches for Influenza Surveillance Philip M. Polgreen,
Yiling Chen, David M. Pennock, and Forrest D. Nelson One study, published ...
Cited by 50 - Related articles - BL Direct - All 17 versions


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