LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com Obesity increases the risk of cardiovascular disease and premature death.
Adipose tissue releases a large number of bioactive mediators that influence not
only body weight homeostasis but also insulin resistance — the core ... Cited by 258 - Related articles - BL Direct - All 6 versions
S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc The prevalence of diabetes mellitus is growing rapidly. It is estimated that
globally the number of adults affected with diabetes will increase from 135
million in 1995 to 300 million by 2025. 1 Patients with diabetes mellitus ... Cited by 136 - Related articles - All 5 versions
- ►ahajournals.org [PDF] JM McGavock, I Lingvay, I Zib, T Tillery, N … - Circulation, 2007 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... A 1 H-Magnetic Resonance Spectroscopy Study Cited by 52 - Related articles - All 5 versions
HS Sacks, JN Fain - American Heart Journal, 2007 - Elsevier We discuss the anatomy, physiology, and pathophysiology of epicardial adipose
tissue and its relationship to coronary atherosclerosis. Epicardial fat stores
triglyceride to supply free fatty acids for myocardial energy production ... Cited by 39 - Related articles - All 30 versions
- ►ahajournals.org J Yang, N Sambandam, X Han, RW Gross, M … - Circulation research, 2007 - Am Heart Assoc Obesity-related diabetes mellitus leads to increased myocardial uptake of fatty
acids (FAs), resulting in a form of cardiac dysfunction referred to as lipotoxic
cardiomyopathy. We have shown previously that chronic activation of the FA- ... Cited by 38 - Related articles - All 6 versions
ED Abel, SE Litwin, G Sweeney - Physiological Reviews, 2008 - Am Physiological Soc The dramatic increase in the prevalence of obesity and its strong association
with cardiovascular disease have resulted in unprecedented interest in
understanding the effects of obesity on the cardiovascular system. A ... Cited by 25 - Related articles - BL Direct - All 3 versions
HE Bays, JM Gonzlez-Campoy, GA Bray, AE … - Expert Review of Cardiovascular Therapy, 2008 - ingentaconnect.com When caloric intake exceeds caloric expenditure, the positive caloric balance
and storage of energy in adipose tissue often causes adipocyte hypertrophy and
visceral adipose tissue accumulation. These pathogenic anatomic ... Cited by 26 - Related articles - All 4 versions
H Bays, C Ballantyne - Future Lipidol., 2006 - Future Medicine In the adipocentric paradigm, fat health affects patient health. Adiposopathy
('pathos' of adipose tissue or fat dysfunction) is more directly associated with
excessive fat-related metabolic disease (EFRMD) than adiposity (increased ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org LS Szczepaniak, RG Victor, L Orci, RH Unger - Circulation Research, 2007 - Am Heart Assoc Until 60 years ago, fatty heart was an accepted clinical entity. Since then, its
very existence has been questioned, despite the fact that 2 of 3 Americans are
now obese or overweight and obesity has been shown to be correlated with ... Cited by 19 - Related articles - All 3 versions
C Wong, TH Marwick - Nature clinical practice. Cardiovascular medicine, 2007 - ncbi.nlm.nih.gov Obesity is becoming a worldwide phenomenon. Myocardial changes associated with
the obese state are increasingly recognized, independent of hypertension,
obstructive sleep apnea and coronary artery disease. The existence of a ... Cited by 17 - Related articles - BL Direct - All 3 versions